Background The circulating metabolome, reflecting underlying cellular processes and
disease biology, has not been fully characterized in patients with idiopathic pulmonary …

Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease of unknown
cause characterised by progressive fibrotic formation in lung tissue. We hypothesise that …

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with significant mortality and
morbidity. Approval of antifibrotic therapy has ameliorated disease progression, but therapy …

Background Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease
characterized by fibrosis and progressive loss of lung function. The pathophysiological …

Background Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of unknown etiology.
Patients present loss of lung function, dyspnea and dry cough. Diagnosis requires …

Interstitial lung diseases (ILDs), also known as diffuse lung diseases, pose a significant
challenge to the respiratory health of individuals worldwide. Among these conditions …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disorder of unknown origin and
the most common interstitial lung disease. It progresses with the recruitment of fibroblasts …

This study leverages a two-sample Mendelian Randomization (MR) approach to explore the
causal relationships between 1,400 metabolites and pulmonary fibrosis, using genetic …

Background The processes that result in progression of idiopathic pulmonary fibrosis (IPF)
remain enigmatic. Moreover, the course of this disease can be highly variable and difficult to …

Idiopathic pulmonary fibrosis (IPF) is a severe lung disease with poor survival that warrants
early and precise diagnosis for timely therapeutic intervention. Despite accumulating …