[HTML][HTML] Memory CD8+ T cell diversity and B cell responses correlate with protection against SARS-CoV-2 following mRNA vaccination
N Brasu, I Elia, V Russo, G Montacchiesi… - Nature …, 2022 - nature.com
Understanding immune responses to SARS-CoV-2 messenger RNA (mRNA) vaccines is of
great interest, principally because of the poor knowledge about the mechanisms of …
great interest, principally because of the poor knowledge about the mechanisms of …
Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination
mRNA vaccines for SARS-CoV-2 have been authorized for emergency use. Despite their
efficacy in clinical trials, data on mRNA vaccine–induced immune responses are mostly …
efficacy in clinical trials, data on mRNA vaccine–induced immune responses are mostly …
mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern
INTRODUCTION Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA
vaccines are highly effective at preventing infection and especially severe disease …
vaccines are highly effective at preventing infection and especially severe disease …
[HTML][HTML] Longitudinal analysis reveals distinct antibody and memory B cell responses in SARS-CoV2 naive and recovered individuals following mRNA vaccination
Novel mRNA vaccines for SARS-CoV2 have been authorized for emergency use and are
currently being administered to millions of individuals worldwide. Despite their efficacy in …
currently being administered to millions of individuals worldwide. Despite their efficacy in …
[HTML][HTML] mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants
In addition to serum immunoglobulins, memory B cell (MBC) generation against severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is another layer of immune …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is another layer of immune …
[HTML][HTML] Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine
We examined antibody and memory B cell responses longitudinally for∼ 9–10 months after
primary 2-dose SARS-CoV-2 mRNA vaccination and 3 months after a 3rd dose. Antibody …
primary 2-dose SARS-CoV-2 mRNA vaccination and 3 months after a 3rd dose. Antibody …
[HTML][HTML] SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells
Although mRNA vaccine efficacy against severe coronavirus disease 2019 remains high,
variant emergence has prompted booster immunizations. However, the effects of repeated …
variant emergence has prompted booster immunizations. However, the effects of repeated …
[HTML][HTML] Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine
V Oberhardt, H Luxenburger, J Kemming, I Schulien… - Nature, 2021 - nature.com
SARS-CoV-2 spike mRNA vaccines,–mediate protection from severe disease as early as ten
days after prime vaccination, when neutralizing antibodies are hardly detectable,–. Vaccine …
days after prime vaccination, when neutralizing antibodies are hardly detectable,–. Vaccine …
[HTML][HTML] mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior …
While mRNA vaccines are proving highly efficacious against SARS-CoV-2, it is important to
determine how booster doses and prior infection influence the immune defense they elicit …
determine how booster doses and prior infection influence the immune defense they elicit …
BNT162b2 vaccination induces durable SARS-CoV-2–specific T cells with a stem cell memory phenotype
G Guerrera, M Picozza, S D'Orso, R Placido… - Science …, 2021 - science.org
Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
effective in preventing hospitalization from severe COVID-19. However, multiple reports of …
effective in preventing hospitalization from severe COVID-19. However, multiple reports of …