Gene therapy is now being applied to the treatment of a wide variety of acquired and
inherited diseases. One of the rate-limiting steps for successful gene therapy is the efficiency …

Viral vector is the most effective means of gene transfer to modify specific cell type or tissue
and can be manipulated to express therapeutic genes. Several virus types are currently …

The efficient delivery of therapeutic genes and appropriate gene expression are the crucial
issues for clinically relevant gene therapy. Viruses are naturally evolved vehicles which …

In the late 1970s, it was predicted that gene therapy would be applied to humans within a
decade. However, despite some success, gene therapy has still not become a routine …

A key factor in the success of gene therapy is the development of gene delivery systems that
are capable of efficient gene transfer in a broad variety of tissues, without causing any …

Gene therapy includes the application of various viral vectors, which represent most types
and families of viruses, suitable for infection of mammalian host cells. Both hereditary …

Within the past decade, gene therapy strategies have come to the forefront of novel
therapeutics. Tremendous advances in vector technology along with deeper understandings …

Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or
at least to improve the clinical status of a patient. One of the basic concepts of gene therapy …

The development of viral vectors for gene therapy has had an interesting and somewhat
tumultuous history but remains the most important avenue tor treatment of a large number of …

Human gene therapy promises to change the practice of medicine by treating the causes of
disease rather than the symptoms. Since the first clinical trial made its debut ten years ago …