Neuroprotective effect of natural products against Alzheimer's disease

MM Essa, RK Vijayan, G Castellano-Gonzalez… - Neurochemical …, 2012 - Springer
Nature has gifted mankind with a plethora of flora-bearing fruits, vegetables and nuts. The
diverse array of bioactive nutrients present in these natural products plays a pivotal role in …

Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options

B Uttara, AV Singh, P Zamboni… - Current …, 2009 - ingentaconnect.com
Free radicals are common outcome of normal aerobic cellular metabolism. In-built
antioxidant system of body plays its decisive role in prevention of any loss due to free …

Oxidative stress in Alzheimer's disease: why did antioxidant therapy fail?

T Persson, BO Popescu… - Oxidative medicine and …, 2014 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia in the elderly, with
increasing prevalence and no disease‐modifying treatment available yet. A remarkable …

[HTML][HTML] Plant-derived bioactive compounds in the management of neurodegenerative disorders: Challenges, future directions and molecular mechanisms involved in …

S Shoaib, MA Ansari, AA Fatease, AY Safhi, U Hani… - Pharmaceutics, 2023 - mdpi.com
Neurodegenerative disorders encompass a wide range of pathological conditions caused
by progressive damage to the neuronal cells and nervous-system connections, which …

Dietary plant polyphenols as the potential drugs in neurodegenerative diseases: current evidence, advances, and opportunities

L Yan, MS Guo, Y Zhang, L Yu, JM Wu… - Oxidative Medicine …, 2022 - Wiley Online Library
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD), are characterized by the progressive degeneration of …

Effects of resveratrol and other polyphenols on the most common brain age-related diseases

F Sarubbo, D Moranta, VJ Asensio… - Current medicinal …, 2017 - ingentaconnect.com
Background: With global increase in elderly population, modern societies must find
strategies to reduce the consequences of aging process; thereby decreasing the incidence …

Bioactive compounds and their derivatives: an insight into prospective phytotherapeutic approach against alzheimer's disease

F Islam, JF Khadija, M Harun-Or-Rashid… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a common neurodegenerative brain disorder that causes
cellular response alterations, such as impaired cholinergic mechanism, amyloid‐beta (Aβ) …

Perspectives on the molecular mediators of oxidative stress and antioxidant strategies in the context of neuroprotection and neurolongevity: an extensive review

S Shohag, S Akhter, S Islam, T Sarker… - Oxidative Medicine …, 2022 - Wiley Online Library
Molecules with at least one unpaired electron in their outermost shell are known as free
radicals. Free radical molecules are produced either within our bodies or by external …

Nutritional approaches to combat oxidative stress in Alzheimer's disease

DA Butterfield, A Castegna, CB Pocernich… - The Journal of nutritional …, 2002 - Elsevier
Alzheimer's disease (AD) brains are characterized by extensive oxidative stress.
Additionally, large depositions of amyloid β-peptide (Aβ) are observed, and many …

Novel promising therapeutics against chronic neuroinflammation and neurodegeneration in Alzheimer's disease

M Venigalla, S Sonego, E Gyengesi… - Neurochemistry …, 2016 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder, characterized by
deposition of amyloid plaques and neurofibrillary tangles, as well as microglial and …