[HTML][HTML] Genome editing of pigs for agriculture and biomedicine

H Yang, Z Wu - Frontiers in Genetics, 2018 - frontiersin.org
Pigs serve as an important agricultural resource and animal model in biomedical studies.
Efficient and precise modification of pig genome by using recently developed gene editing …

Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases

J Yao, J Huang, J Zhao - Human genetics, 2016 - Springer
Pigs have anatomical, physiological and genomic characteristics that make them highly
suitable for modeling human diseases. Genetically modified (GM) pig models of human …

Use of gene-editing technology to introduce targeted modifications in pigs

J Ryu, RS Prather, K Lee - Journal of animal science and biotechnology, 2018 - Springer
Pigs are an important resource in agriculture and serve as a model for human diseases. Due
to their physiological and anatomical similarities with humans, pigs can recapitulate …

Genome editing for disease resistance in pigs and chickens

C Proudfoot, S Lillico, C Tait-Burkard - Animal Frontiers, 2019 - academic.oup.com
• Methods for genome editing have developed over the past decades, making the
technology more efficient and specific.• Technology to generate edited pigs and chickens is …

Farm animals are important biomedical models

DL Hamernik - Animal Frontiers, 2019 - academic.oup.com
This issue of Animal Frontiers,“Farm animals are important biomedical models,” describes
several examples in which cattle, sheep, pigs, or chickens provide an excellent …

Genome editing in livestock: Are we ready for a revolution in animal breeding industry?

J Ruan, J Xu, RY Chen-Tsai, K Li - Transgenic research, 2017 - Springer
Genome editing is a powerful technology that can efficiently alter the genome of organisms
to achieve targeted modification of endogenous genes and targeted integration of …

Current status of the application of gene editing in pigs

F Tanihara, M Hirata, T Otoi - Journal of Reproduction and …, 2021 - jstage.jst.go.jp
Genetically modified animals, especially rodents, are widely used in biomedical research.
However, non-rodent models are required for efficient translational medicine and preclinical …

Genetic modifications of pigs for medicine and agriculture

JJ Whyte, RS Prather - Molecular reproduction and …, 2011 - Wiley Online Library
Genetically modified swine hold great promise in the fields of agriculture and medicine.
Currently, these swine are being used to optimize production of quality meat, to improve our …

Cytosine base editor (hA3A-BE3-NG)-mediated multiple gene editing for pyramid breeding in pigs

Y Wang, D Bi, G Qin, R Song, J Yao, C Cao… - Frontiers in …, 2020 - frontiersin.org
Pig is an important agricultural economic animal, providing large amount of meat products.
With the development of functional genomics and bioinformatics, lots of genes and …

Current progress of genome editing in livestock

K Lee, K Uh, K Farrell - Theriogenology, 2020 - Elsevier
Historically, genetic engineering in livestock proved to be challenging. Without stable
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …