Advances in genotyping and sequencing a little over a decade ago have greatly enhanced
our ability to read the genomes of livestock, leading to the development and application of …

Progress in genetic engineering over the past few decades has made it possible to develop
methods that have led to the production of transgenic animals. The development of …

Genetically engineered sheep and goats represent useful models applied to proof of
concepts, large-scale production of novel products or processes, and improvement of animal …

Targeted modification of the pig genome can be challenging. Recent applications of the
CRISPR/Cas9 system hold promise for improving the efficacy of genome editing. When a …

Pig shows multiple superior characteristics in anatomy, physiology, and genome that have
made this species to be more suitable models for human diseases, especially for …

Background Anatomic and physiological similarities to the human make swine an excellent
large animal model for human health and disease. Methods Cloning from a modified …

The prospect of genome editing offers a number of promising opportunities for livestock
breeders. Firstly, these tools can be used in functional genomics to elucidate gene function …

The sophistication and revolution in genome editing and manipulation have revolutionized
livestock by harvesting essential biotechnological products such as drugs, proteins, and …

Background The simplicity of the CRISPR/Cas9 system has enabled its widespread
applications in generating animal models, functional genomic screening and in treating …

Contents In the last decade, the research community has witnessed a blooming of targeted
genome editing tools and applications. Novel programmable DNA nucleases such as zinc …