Purpose: To study the effect of grape seed proanthocyanidin (GSP) on left ventricular
remodeling in spontaneously hypertensive rats, and the underlying mechanism. Methods …

Arterial remodeling is a pathogenic occurrence during hypertension and, in turn, is closely
associated with the development and complications of hypertension. Grape seed …

Cardiovascular remodeling, as a hallmark of hypertension-induced pathophysiology, causes
substantial cardiovascular morbidity and mortality. There is increasing evidence that has …

The aim of this study was to clarify whether grape seed proanthocyanidins extracts (GSPE)
were therapeutic agents against diabetic cardiomyopathy. After diabetes was induced by …

Hesperidin is a major flavonoid isolated from citrus fruits that exhibits several biological
activities. This study aims to evaluate the effect of hesperidin on cardiovascular remodeling …

Grape seed proanthocyanidin (GSP) bears a very powerful antioxidant effects. Studies
demonstrated that proanthocyanidins protect against free radicals mediated cardiovascular …

Objectives: Cardiac hypertrophy is a leading cause for heart failure which in turn has a high
mortality rate. Hesperidin (HES) is a flavanone glycoside with agonistic activity on …

Vascular remodeling is a primary contributor to the initiation and development of
hypertension, which has a pathological association with subsequent multi-organ damage …

PURPOSE: To investigate whether grape seed proanthocyanidins (GSP) might protect the
heart against myocardial injury (MI) induced by isoproterenol (ISO), in a rat model …

Recent studies indicate that chronic ouabain treatment leads to hypertension and
hypertensive vascular remodeling. Grape seed proanthocyanidin extract (GSPE) has been …