[HTML][HTML] Interleukin-22 in the pathogenesis and potential treatment of liver diseases

S Yin, D Feng - Liver Research, 2017 - Elsevier
Abstract Interleukin (IL)-22, a member of the IL-10 cytokine family, plays critical roles in
tissue repair and host defense. IL-22 binds to its hetereodimeric receptor (R) composed of IL …

[HTML][HTML] Interleukin 22 in liver injury, inflammation and cancer

Y Wu, J Min, C Ge, J Shu, D Tian, Y Yuan… - International Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Interleukin 22 (IL-22), a member of the IL-10 cytokine family and is an emerging
CD4+ Th cytokine that plays an important role in anti-microbial defense, homeostasis and …

[HTML][HTML] Role of interleukin-22 in liver diseases

C Pan, J Tang, X Wang, F Wu, J Ge, F Chen - Inflammation Research, 2014 - Springer
Abstract Introduction Interleukin (IL)-22, originally referred to as IL-TIF for IL-10-related T cell-
derived inducible factor, is a member of the IL-10-like cytokine family. IL-22 is highly …

[HTML][HTML] The interleukin-20 cytokine family in liver disease

E Caparrós, R Francés - Frontiers in Immunology, 2018 - frontiersin.org
The three main causes of inflammation and chronic injury in the liver are viral hepatitis,
alcohol consumption, and non-alcoholic steatohepatitis, all of which can lead to liver fibrosis …

[HTML][HTML] The role of interleukin-20 in liver disease: Functions, mechanisms and clinical applications

K Wang, HQ Zhan, Y Hu, ZY Yuan, JF Yang, DS Yang… - Heliyon, 2024 - cell.com
Liver disease is a severe public health concern worldwide. There is a close relationship
between the liver and cytokines, and liver inflammation from a variety of causes leads to the …

How Does Interleukin‐22 Mediate Liver Regeneration and Prevent Injury and Fibrosis?

MB Khawar, F Azam, N Sheikh… - Journal of Immunology …, 2016 - Wiley Online Library
Interleukin‐22 (IL‐22) is a pluripotent T cell‐derived cytokine which is a member of IL‐10
cytokine family. It is the only interleukin produced by immune cells but does not target …

Type 3 cytokines in liver fibrosis and liver cancer

MF Molina, MN Abdelnabi, T Fabre, NH Shoukry - Cytokine, 2019 - Elsevier
The type 3 cytokines IL-17 and IL-22 play a crucial, well synchronized physiological role in
wound healing and repairing tissue damage due to infections or injury at barrier surfaces …

[PDF][PDF] Interleukin‐22, interleukin‐17, and other cytokines: A wall is coming down

P Bertolino - Hepatology, 2008 - Wiley Online Library
Abstract The cytokine interleukin-22 (IL-22) is primarily expressed by T helper 17 (Th17)
CD4 (+) T cells and is highly upregulated during chronic inflammatory diseases. IL-22 …

Interplay of interleukin‐22 and its binding protein in controlling liver scarring

B Gao - Hepatology, 2015 - journals.lww.com
Interleukin (IL)-22, which was discovered in 2000 as a T-cell-derived cytokine, is probably
the only cytokine produced by immune cells (eg, T helper [Th] 17 cells, Th22 cells, activated …

Interleukin-22 promotes the proliferation and migration of hepatocellular carcinoma cells via the phosphoinositide 3-kinase (PI3K/AKT) signaling pathway

F Mansur, T Arshad, V Liska, S Manzoor - Molecular Biology Reports, 2023 - Springer
Abstract Background Interleukin-22 (IL-22) is a pro-inflammatory cytokine released during
the immune response in chronic liver injury. Although IL-22 mediates tissue regeneration, its …