Abstract Multidrug resistance 1 (MDR1) is a transmembrane transporter on the cell
membrane. As an ATP‑dependent efflux pump, MDR1 is mainly responsible for the …

Abstract The C3435T (rs1045642) polymorphism, located in multi-drug resistance gene 1
(MDR1), has demonstrated its role in decreasing the P-gp activity level which is related to …

Background: Breast cancer is the leading cause of cancer death among women and the
second in humans worldwide. Many published studies have suggested an association …

Objective: Breast cancer is known as the most prevalent cancer among women and the
second most common cancer in the world. Different studies mentioned the …

Breast cancer (BC) is the most common cancer among women in the world. The human
multidrug resistance 1 gene (MDR1) is potentially an important gene influencing the …

The human multidrug resistance 1 gene (MDR1) is an important candidate gene influencing
the susceptibility to various diseases, including breast cancer. The object of this study was to …

The multidrug resistance 1 gene (MDR1) is an important candidate gene for influencing
breast cancer susceptibility. This study aimed to evaluate the association between MDR1 …

The multidrug resistance gene 1 (MDR1) encodes a membrane-bound phosphoglycoprotein
(P-gp). It functions as a transmembrane efflux pump for various structurally unrelated …

The human multidrug resistance gene 1 (MDR-1) encodes a plasma membrane P-
glycoprotein (P-gp) that functions as the transmembrane efflux pump for various structurally …

Objective: The most common malignancy in women is breast cancer worldwide. Previous
studies performed in different populations have suggested an association between Multi …