Adiponectin: a key adipocytokine in metabolic syndrome

Y Okamoto, S Kihara, T Funahashi… - Clinical …, 2006 - portlandpress.com
The metabolic syndrome, a cluster of metabolic disorders often associated with visceral
obesity, increases cardiovascular mortality and morbidity. As the body's largest endocrine …

Adiponectin: a potential therapeutic target for metabolic syndrome

AA Ghadge, AA Khaire, AA Kuvalekar - Cytokine & growth factor reviews, 2018 - Elsevier
Adiponectin is an important adipocytokine secreted chiefly by fat containing adipocytes, and
plays a crucial role in glucose and lipid metabolism, inflammation and oxidative stress …

Adiponectin, a unique adipocyte-derived factor beyond hormones

N Maeda, T Funahashi, Y Matsuzawa, I Shimomura - Atherosclerosis, 2020 - Elsevier
Visceral fat accumulation has a marked impact on atherosclerotic cardiovascular diseases
and metabolic syndrome clustering diabetes, dyslipidemia, and hypertension. Adiponectin …

Adiponectin and the metabolic syndrome: mechanisms mediating risk for metabolic and cardiovascular disease

C Lara-Castro, Y Fu, BH Chung… - Current opinion in …, 2007 - journals.lww.com
Recent studies emphasize the role played by adiponectin in the homeostasis of adipose
tissue and in the pathogenesis of the metabolic syndrome, type 2 diabetes, and …

Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular disease

Y Matsuzawa - Atherosclerosis supplements, 2005 - Elsevier
Adiponectin is the most abundant adipose-specific protein. Its expression is reduced in
obesity, insulin resistance and type 2 diabetes, and plasma concentrations are inversely …

Adiponectin: a key player in obesity related disorders

Y Matsuzawa - Current pharmaceutical design, 2010 - ingentaconnect.com
Recent studies revealed that adipose tissue is not only an energy storing organ, but is a kind
of endocrine organ which secretes a variety of bioactive substances, so-called adipokines or …

Adiponectin–a key adipokine in the metabolic syndrome

JP Whitehead, AA Richards, IJ Hickman… - Diabetes, Obesity …, 2006 - Wiley Online Library
Adiponectin is a recently described adipokine that has been recognized as a key regulator
of insulin sensitivity and tissue inflammation. It is produced by adipose tissue (white and …

Adiponectin: regulation of its production and its role in human diseases

A Shehzad, W Iqbal, O Shehzad, YS Lee - Hormones, 2012 - Springer
Adiponectin is a white and brown adipose tissue hormone, also known as gelatin-binding
protein-28 (GBP28), AdipoQ, adipocyte complement-related protein (ACRP30), or apM1 …

Physiological, pharmacological, and nutritional regulation of circulating adiponectin concentrations in humans

MM Swarbrick, PJ Havel - Metabolic syndrome and related …, 2008 - liebertpub.com
Adiponectin is an adipocyte hormone that links visceral adiposity with insulin resistance and
atherosclerosis. It is unique among adipocyte-derived hormones in that its circulating …

Adiponectin–journey from an adipocyte secretory protein to biomarker of the metabolic syndrome

ME Trujillo, PE Scherer - Journal of internal medicine, 2005 - Wiley Online Library
Adiponectin is an adipocyte‐derived hormone that was discovered in 1995. Unlike leptin,
which was identified around the same time, the clinical relevance of adiponectin remained …