Breakage of hydrophobic contacts limits the rate of passive lipid exchange between membranes

JR Rogers, PL Geissler - The Journal of Physical Chemistry B, 2020 - ACS Publications
The maintenance of heterogeneous lipid compositions among cellular membranes is key to
biological function. Yet, even the simplest process that could be responsible for maintaining …

Membrane hydrophobicity determines the activation free energy of passive lipid transport

JR Rogers, GE Garcia, PL Geissler - Biophysical journal, 2021 - cell.com
The collective behavior of lipids with diverse chemical and physical features determines a
membrane's thermodynamic properties. Yet, the influence of lipid physicochemical …

A microscopic view of phospholipid insertion into biological membranes

JV Vermaas, E Tajkhorshid - The Journal of Physical Chemistry B, 2014 - ACS Publications
Understanding the process of membrane insertion is an essential step in developing a
detailed mechanism, for example, for peripheral membrane protein association and …

Exploring transmembrane diffusion pathways with molecular dynamics

Y Wang, SA Shaikh, E Tajkhorshid - Physiology, 2010 - journals.physiology.org
Transmembrane exchange of materials is a fundamental process in biology. Molecular
dynamics provides a powerful method to investigate in great detail various aspects of the …

Chemically induced phospholipid translocation across biological membranes

AA Gurtovenko, OI Onike, J Anwar - Langmuir, 2008 - ACS Publications
Chemical means of manipulating the distribution of lipids across biological membranes is of
considerable interest for many biomedical applications as a characteristic lipid distribution is …

Lipid membranes and reactions at lipid interfaces: theory, experiments, and applications

AN Bondar, S Keller - The Journal of Membrane Biology, 2018 - Springer
Lipid membranes that surround each biological cell and its various compartments host
chemical reactions of paramount importance for the cell. Proteins embedded in the lipid …

Dehydration of Lipid Membranes Drives Redistribution of Cholesterol Between Lateral Domains

H Orlikowska-Rzeznik, E Krok… - The Journal of …, 2024 - ACS Publications
Cholesterol-rich lipid rafts are found to facilitate membrane fusion, central to processes like
viral entry, fertilization, and neurotransmitter release. While the fusion process involves local …

Lateral diffusion in lipid membranes through collective flows

E Falck, T Róg, M Karttunen… - Journal of the American …, 2008 - ACS Publications
There is no comprehensive model for the dynamics of cellular membranes. Even
mechanisms of basic dynamic processes, such as lateral diffusion of lipids, are poorly …

Membrane mixer: a toolkit for efficient shuffling of lipids in heterogeneous biological membranes

G Licari, S Dehghani-Ghahnaviyeh… - Journal of chemical …, 2022 - ACS Publications
Molecular dynamics (MD) simulations of biological membranes have achieved such levels
of sophistication that are commonly used to predict unresolved structures and various …

Coupled diffusion in lipid bilayers upon close approach

S Pronk, E Lindahl, PM Kasson - Journal of the American …, 2015 - ACS Publications
Biomembrane interfaces create regions of slowed water dynamics in their vicinity. When two
lipid bilayers come together, this effect is further accentuated, and the associated slowdown …