Lactobacillus Modulates Chlamydia Infectivity and Genital Tract Pathology in vitro and in vivo

H Chen, S Min, L Wang, L Zhao, F Luo, W Lei… - Frontiers in …, 2022 - frontiersin.org
Since we previously reported that women infected with chlamydia had a significant overall
reduction in Lactobacillus in the vagina microbiota as compared to those uninfected …

Lactobacilli Inactivate Chlamydia trachomatis through Lactic Acid but Not H2O2

Z Gong, Y Luna, P Yu, H Fan - PloS one, 2014 - journals.plos.org
Lactobacillus species dominate the microbiome in the lower genital tract of most
reproductive-age women. Producing lactic acid and H2O2, lactobacilli are believed to play …

Effects of vaginal lactobacilli in Chlamydia trachomatis infection

P Mastromarino, M Di Pietro, G Schiavoni… - International Journal of …, 2014 - Elsevier
Increasing evidence indicates that abnormal vaginal flora lacking lactobacilli facilitates the
acquisition of several sexually transmitted diseases including Chlamydia trachomatis. C …

Lactobacillus crispatus BC5 Interferes With Chlamydia trachomatis Infectivity Through Integrin Modulation in Cervical Cells

C Parolin, G Frisco, C Foschi, B Giordani… - Frontiers in …, 2018 - frontiersin.org
Lactobacilli play a crucial role in maintaining the ecological equilibrium of the vaginal niche,
preventing the colonization of exogenous microorganisms. Although many studies have …

Lactobacillus crispatus inhibits the infectivity of Chlamydia trachomatis elementary bodies, in vitro study

P Nardini, RA Ñahui Palomino, C Parolin, L Laghi… - Scientific reports, 2016 - nature.com
Lactobacillus species dominate the vaginal microbiota of healthy reproductive-age women
and protect the genitourinary tract from the attack of several infectious agents. Chlamydia …

Lactobacilli–lactoferrin interplay in Chlamydia trachomatis infection

R Sessa, M Di Pietro, S Filardo, A Bressan… - Pathogens and …, 2017 - academic.oup.com
In the cervicovaginal microenvironment, lactobacilli are known to protect against genital
infections and, amongst the host defence compounds, lactoferrin has recently acquired …

Vaginal Lactobacillus Inhibits HIV-1 Replication in Human Tissues Ex Vivo

RA Ñahui Palomino, S Zicari, C Vanpouille… - Frontiers in …, 2017 - frontiersin.org
Lactobacillus species, which dominate vaginal microbiota of healthy reproductive-age
women, lower the risks of sexually transmitted infections, including the risk of human …

Lactobacillus iners-dominated vaginal microbiota is associated with increased susceptibility to Chlamydia trachomatis infection in Dutch women: a case–control study

R Van Houdt, B Ma, SM Bruisten… - Sexually transmitted …, 2018 - sti.bmj.com
Introduction This prospective study aimed to study the composition and structure of the
vaginal microbiota prior to Chlamydia trachomatis infection. Methods A nested case–control …

[PDF][PDF] The cervicovaginal microbiota-host interaction modulates Chlamydia trachomatis infection. mBio 10: e01548-19

VL Edwards, SB Smith, EJ McComb, J Tamarelle, B Ma… - 2019 - newswise.com
The mechanism (s) by which Lactobacillus-dominated cervicovaginal microbiota provide a
barrier to Chlamydia trachomatis infection remain (s) unknown. Here we evaluate the impact …

Epidemiologic evidence on the role of Lactobacillus iners in sexually transmitted infections and bacterial vaginosis: a series of systematic reviews and meta-analyses

KA Carter, MD Fischer, MI Petrova… - Sexually transmitted …, 2023 - journals.lww.com
Although Lactobacillus crispatus–dominated vaginal microbiotas are thought to protect
against bacterial vaginosis (BV) and sexually transmitted infections, the role of Lactobacillus …