Pigs are an important resource in agriculture and serve as a model for human diseases. Due
to their physiological and anatomical similarities with humans, pigs can recapitulate …

Pigs serve as an important agricultural resource and animal model in biomedical studies.
Efficient and precise modification of pig genome by using recently developed gene editing …

Genetically modified animals, especially rodents, are widely used in biomedical research.
However, non-rodent models are required for efficient translational medicine and preclinical …

Pigs have anatomical, physiological and genomic characteristics that make them highly
suitable for modeling human diseases. Genetically modified (GM) pig models of human …

Abstract Genome/gene-editing (GE) techniques, characterized by a low technological
barrier, high efficiency, and broad application among organisms, are now being employed …

Pigs are an important resource for meat production and serve as a model for human
diseases. Due to their physiological and anatomical similarities to humans, these animals …

Historically, genetic engineering in livestock proved to be challenging. Without stable
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …

The production of transgenic farm animals (eg, cattle) via genome engineering for the gain
or loss of gene functions is an important undertaking. In the initial stages of genome …

Genetically modified pigs for biomedical applications have been mainly generated using the
somatic cell nuclear transfer technique; however, this approach requires complex …

The domestic pig has been widely used as an important large animal model. Precise and
efficient genetic modification in pig provides a great promise in biomedical research …