Effects of losartan, atorvastatin, and aspirin on blood pressure and gut microbiota in spontaneously hypertensive rats

S Dong, Q Liu, X Zhou, Y Zhao, K Yang, L Li, D Zhu - Molecules, 2023 - mdpi.com
Many studies have shown that alterations in the gut microbiota are associated with
hypertension. Our study aimed to observe the characteristics of the gut microbiota in …

Gut microbiota and hypertension: association, mechanisms and treatment

Z Yang, Q Wang, Y Liu, L Wang, Z Ge, Z Li… - Clinical and …, 2023 - Taylor & Francis
Objectives Hypertension is one of the most important risk factors for cardio-cerebral vascular
diseases, which brings a heavy economic burden to society and becomes a major public …

Lactobacillus induced by irbesartan on spontaneously hypertensive rat contribute to its antihypertensive effect

Y Xiong, Y He, Z Chen, T Wu, Y Xiong… - Journal of …, 2024 - journals.lww.com
Objective: Hypertension is linked to gut dysbiosis. Here, the impact of the angiotensin
receptor antagonist irbesartan on the gut microbiota of spontaneously hypertensive rats …

Alterations in the gut microbiota can elicit hypertension in rats

S Adnan, JW Nelson, NJ Ajami… - Physiological …, 2017 - journals.physiology.org
Gut dysbiosis has been linked to cardiovascular diseases including hypertension. We tested
the hypothesis that hypertension could be induced in a normotensive strain of rats or …

Hypotensive effect of captopril on deoxycorticosterone acetate-salt-induced hypertensive rat is associated with gut microbiota alteration

H Wu, TYC Lam, TF Shum, TY Tsai, J Chiou - Hypertension Research, 2022 - nature.com
The role of the gut microbiota in various metabolic diseases has been widely studied. This
study aims to test the hypothesis that gut microbiota dysbiosis is associated with DOCA-salt …

Alterations of the gut microbiome in hypertension

Q Yan, Y Gu, X Li, W Yang, L Jia, C Chen… - Frontiers in cellular …, 2017 - frontiersin.org
Introduction: Human gut microbiota is believed to be directly or indirectly involved in
cardiovascular diseases and hypertension. However, the identification and functional status …

Gut microbiota and host plasma metabolites in association with blood pressure in Chinese adults

Y Wang, H Wang, AG Howard, MCB Tsilimigras… - …, 2021 - Am Heart Assoc
Animal studies have revealed gut microbial and metabolic pathways of blood pressure (BP)
regulation, yet few epidemiological studies have collected microbiota and metabolomics …

Gut microbiota dysbiosis contributes to the development of hypertension

J Li, F Zhao, Y Wang, J Chen, J Tao, G Tian, S Wu… - Microbiome, 2017 - Springer
Background Recently, the potential role of gut microbiome in metabolic diseases has been
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …

Intestinal microbiota by angiotensin receptor blocker therapy exerts protective effects against hypertensive damages

J Li, SY Wang, KX Yan, P Wang, J Jiao, YD Wang… - Imeta, 2024 - Wiley Online Library
Dysbiosis of the gut microbiota has been implicated in hypertension, and drug–host–
microbiome interactions have drawn considerable attention. However, the influence of …

Probiotic yogurt blunts the increase of blood pressure in spontaneously hypertensive rats via remodeling of the gut microbiota

CY Kong, ZM Li, YQ Mao, HL Chen, W Hu, B Han… - Food & Function, 2021 - pubs.rsc.org
Dietary intake of probiotic yogurt, which has beneficial effects on intestinal microecology, is
associated with a lower incidence of hypertension. Recent studies have shown that the gut …