Characterization of the human myocardial proteome in inflammatory dilated cardiomyopathy by label-free quantitative shotgun proteomics of heart biopsies
E Hammer, M Goritzka, S Ameling, K Darm… - Journal of proteome …, 2011 - ACS Publications
Dilated cardiomyopathy (DCM) is characterized by contractile dysfunction leading to heart
failure. The molecular changes in the human heart associated with this disease have so far …
failure. The molecular changes in the human heart associated with this disease have so far …
Proteomics in heart failure: top-down or bottom-up?
ZR Gregorich, YH Chang, Y Ge - Pflügers Archiv-European Journal of …, 2014 - Springer
The pathophysiology of heart failure (HF) is diverse, owing to multiple etiologies and
aberrations in a number of cellular processes. Therefore, it is essential to understand how …
aberrations in a number of cellular processes. Therefore, it is essential to understand how …
Predicting left ventricular remodeling after a first myocardial infarction by plasma proteome analysis
F Pinet, O Beseme, C Cieniewski‐Bernard… - …, 2008 - Wiley Online Library
Recent improvements in therapeutic strategies did not prevent left ventricular remodeling
(LVR), which remains a common event (30%) after acute myocardial infarction (AMI). We …
(LVR), which remains a common event (30%) after acute myocardial infarction (AMI). We …
Using peripheral blood mononuclear cells to determine proteome profiles in human cardiac failure
A Mazzola, R Cianti, L Bini, A Armini… - European journal of …, 2008 - Wiley Online Library
Background: In chronic heart failure (CHF), peripheral blood mononuclear cells (PBMC)
might undergo structural and/or functional alterations as a consequence of the development …
might undergo structural and/or functional alterations as a consequence of the development …
[HTML][HTML] Dynamic adaptation of myocardial proteome during heart failure development
Heart failure (HF) development is characterized by huge structural changes that are crucial
for disease progression. Analysis of time dependent global proteomic adaptations during HF …
for disease progression. Analysis of time dependent global proteomic adaptations during HF …
[HTML][HTML] Multimarker proteomic profiling for the prediction of cardiovascular mortality in patients with chronic heart failure
Risk stratification of patients with systolic chronic heart failure (HF) is critical to better identify
those who may benefit from invasive therapeutic strategies such as cardiac transplantation …
those who may benefit from invasive therapeutic strategies such as cardiac transplantation …
Physiological proteomics of heart failure
J O'Reilly, ML Lindsey, JA Baugh - Current Opinion in Physiology, 2018 - Elsevier
Highlights•The complex pathophysiology of heart failure is summarized.•This article reviews
the use of proteomics to elucidate responses to cardiac injury.•Proteomic analyses of tissue …
the use of proteomics to elucidate responses to cardiac injury.•Proteomic analyses of tissue …
Global plasma protein profiling reveals DCM characteristic protein signatures
To identify potential biomarkers supporting better phenotyping and to improve
understanding of the pathophysiology of dilated cardiomyopathy (DCM), this study …
understanding of the pathophysiology of dilated cardiomyopathy (DCM), this study …
[HTML][HTML] Plasma proteomic analysis of association between atrial fibrillation, coronary microvascular disease and heart failure
G Dixit, J Blair, C Ozcan - American Journal of Cardiovascular …, 2022 - ncbi.nlm.nih.gov
The clinical association between atrial fibrillation (AF), coronary microvascular disease
(CMD) and heart failure with preserved ejection fraction (HFpEF) is highly prevalent …
(CMD) and heart failure with preserved ejection fraction (HFpEF) is highly prevalent …
[HTML][HTML] Urinary proteomic signature in acute decompensated heart failure: advances into molecular pathophysiology
E Diaz-Riera, M García-Arguinzonis, L López… - International Journal of …, 2022 - mdpi.com
Acute decompensated heart failure (ADHF) is a life-threatening clinical syndrome involving
multi-organ function deterioration. ADHF results from multifaceted, dysregulated pathways …
multi-organ function deterioration. ADHF results from multifaceted, dysregulated pathways …