Will “CLINICAL PROTEOMICS” lead to the discovery of new biomarkers for dilated cardiomyopathy (DCM)?

S Saha, V Sarohi, T Basak - Journal of Proteins and Proteomics, 2023 - Springer
Dilated cardiomyopathy (DCM) is one of the leading causes of heart failure worldwide. DCM
is defined as the dilatation and thinning of heart muscles leading to enlargement of the …

Multimarker proteomic profiling for the prediction of cardiovascular mortality in patients with chronic heart failure

G Lemesle, F Maury, O Beseme, L Ovart, P Amouyel… - PLoS …, 2015 - journals.plos.org
Risk stratification of patients with systolic chronic heart failure (HF) is critical to better identify
those who may benefit from invasive therapeutic strategies such as cardiac transplantation …

Dynamic adaptation of myocardial proteome during heart failure development

J Rüdebusch, A Benkner, A Poesch, M Dörr, U Völker… - PLoS …, 2017 - journals.plos.org
Heart failure (HF) development is characterized by huge structural changes that are crucial
for disease progression. Analysis of time dependent global proteomic adaptations during HF …

Physiological proteomics of heart failure

J O'Reilly, ML Lindsey, JA Baugh - Current Opinion in Physiology, 2018 - Elsevier
Highlights•The complex pathophysiology of heart failure is summarized.•This article reviews
the use of proteomics to elucidate responses to cardiac injury.•Proteomic analyses of tissue …

Urinary proteomic signature in acute decompensated heart failure: advances into molecular pathophysiology

E Diaz-Riera, M García-Arguinzonis, L López… - International Journal of …, 2022 - mdpi.com
Acute decompensated heart failure (ADHF) is a life-threatening clinical syndrome involving
multi-organ function deterioration. ADHF results from multifaceted, dysregulated pathways …

[HTML][HTML] Plasma proteomic analysis of association between atrial fibrillation, coronary microvascular disease and heart failure

G Dixit, J Blair, C Ozcan - American Journal of Cardiovascular …, 2022 - ncbi.nlm.nih.gov
The clinical association between atrial fibrillation (AF), coronary microvascular disease
(CMD) and heart failure with preserved ejection fraction (HFpEF) is highly prevalent …

Identification of potentially critical genes in the development of heart failure after ST‐segment elevation myocardial infarction (STEMI)

C Qian, D Chang, H Li, Y Wang - Journal of cellular …, 2019 - Wiley Online Library
Heart failure (HF) remains a common complication after acute ST‐segment elevation
myocardial infarction (STEMI). Here, we aim to identify critical genes related to the …

[HTML][HTML] Proteome-wide Characterization and Pathophysiology Correlation in Non-ischemic Cardiomyopathies

S Lee, DG Jang, YJ Kyoung, J Kim, ES Kim… - Korean Circulation …, 2023 - e-kcj.org
Methods Comparative extensive proteomic analysis of the myocardium was performed in
nine patients with biopsy-proven non-ischemic cardiomyopathies (3 dilated cardiomyopathy …

Global plasma protein profiling reveals DCM characteristic protein signatures

MA Feig, C Pop, G Bhardwaj, PK Sappa, M Dörr… - Journal of …, 2019 - Elsevier
To identify potential biomarkers supporting better phenotyping and to improve
understanding of the pathophysiology of dilated cardiomyopathy (DCM), this study …

Finding a needle in a haystack: proteomics in heart failure

SA Michelhaugh, JL Januzzi Jr - Basic to Translational Science, 2020 - jacc.org
Circulating protein biomarkers provide information regarding pathways in heart failure (HF)
and can add important value to clinicians. Advancements in proteomics allow researchers to …