Will “CLINICAL PROTEOMICS” lead to the discovery of new biomarkers for dilated cardiomyopathy (DCM)?
Dilated cardiomyopathy (DCM) is one of the leading causes of heart failure worldwide. DCM
is defined as the dilatation and thinning of heart muscles leading to enlargement of the …
is defined as the dilatation and thinning of heart muscles leading to enlargement of the …
Multimarker proteomic profiling for the prediction of cardiovascular mortality in patients with chronic heart failure
Risk stratification of patients with systolic chronic heart failure (HF) is critical to better identify
those who may benefit from invasive therapeutic strategies such as cardiac transplantation …
those who may benefit from invasive therapeutic strategies such as cardiac transplantation …
Dynamic adaptation of myocardial proteome during heart failure development
Heart failure (HF) development is characterized by huge structural changes that are crucial
for disease progression. Analysis of time dependent global proteomic adaptations during HF …
for disease progression. Analysis of time dependent global proteomic adaptations during HF …
Physiological proteomics of heart failure
J O'Reilly, ML Lindsey, JA Baugh - Current Opinion in Physiology, 2018 - Elsevier
Highlights•The complex pathophysiology of heart failure is summarized.•This article reviews
the use of proteomics to elucidate responses to cardiac injury.•Proteomic analyses of tissue …
the use of proteomics to elucidate responses to cardiac injury.•Proteomic analyses of tissue …
Urinary proteomic signature in acute decompensated heart failure: advances into molecular pathophysiology
E Diaz-Riera, M García-Arguinzonis, L López… - International Journal of …, 2022 - mdpi.com
Acute decompensated heart failure (ADHF) is a life-threatening clinical syndrome involving
multi-organ function deterioration. ADHF results from multifaceted, dysregulated pathways …
multi-organ function deterioration. ADHF results from multifaceted, dysregulated pathways …
[HTML][HTML] Plasma proteomic analysis of association between atrial fibrillation, coronary microvascular disease and heart failure
G Dixit, J Blair, C Ozcan - American Journal of Cardiovascular …, 2022 - ncbi.nlm.nih.gov
The clinical association between atrial fibrillation (AF), coronary microvascular disease
(CMD) and heart failure with preserved ejection fraction (HFpEF) is highly prevalent …
(CMD) and heart failure with preserved ejection fraction (HFpEF) is highly prevalent …
Identification of potentially critical genes in the development of heart failure after ST‐segment elevation myocardial infarction (STEMI)
C Qian, D Chang, H Li, Y Wang - Journal of cellular …, 2019 - Wiley Online Library
Heart failure (HF) remains a common complication after acute ST‐segment elevation
myocardial infarction (STEMI). Here, we aim to identify critical genes related to the …
myocardial infarction (STEMI). Here, we aim to identify critical genes related to the …
[HTML][HTML] Proteome-wide Characterization and Pathophysiology Correlation in Non-ischemic Cardiomyopathies
S Lee, DG Jang, YJ Kyoung, J Kim, ES Kim… - Korean Circulation …, 2023 - e-kcj.org
Methods Comparative extensive proteomic analysis of the myocardium was performed in
nine patients with biopsy-proven non-ischemic cardiomyopathies (3 dilated cardiomyopathy …
nine patients with biopsy-proven non-ischemic cardiomyopathies (3 dilated cardiomyopathy …
Global plasma protein profiling reveals DCM characteristic protein signatures
To identify potential biomarkers supporting better phenotyping and to improve
understanding of the pathophysiology of dilated cardiomyopathy (DCM), this study …
understanding of the pathophysiology of dilated cardiomyopathy (DCM), this study …
Finding a needle in a haystack: proteomics in heart failure
SA Michelhaugh, JL Januzzi Jr - Basic to Translational Science, 2020 - jacc.org
Circulating protein biomarkers provide information regarding pathways in heart failure (HF)
and can add important value to clinicians. Advancements in proteomics allow researchers to …
and can add important value to clinicians. Advancements in proteomics allow researchers to …