Purpose: Depletion of major blood proteins is one of the most promising approaches to
accessing low abundance biomarkers for proteomics studies. The use of combinatorial …

Background The precise mechanisms leading to the development of heart failure with
preserved ejection fraction (HFpEF) remain incompletely defined. In this study, an integrative …

Cardiac hypertrophy, interstitial fibrosis, and cardiac dysfunction ultimately lead to cardiac
failure. Cardiac failure is one of the major causes of heart disease and death in our society …

Background: Extensive evidence from single-center studies indicates that a subset of
patients with chronic advanced heart failure (HF) undergoing left ventricular assist device …

The rapid increase in the prevalence of chronic heart failure (CHF) worldwide underscores
an urgent need to identify biomarkers for the early detection of CHF. Post-translational …

Circulating proteins may provide insights into the varying biological mechanisms involved in
heart failure (HF) with preserved ejection fraction (HFpEF) and reduced ejection fraction …

The development of heart failure (HF) is characterized by progressive alteration of left
ventricle structure and function. Previous works on proteomic analysis in cardiac tissue from …

Background—Underlying mechanisms in heart failure (HF) with preserved ejection fraction
remain unknown. We investigated cardiovascular plasma biomarkers in HF with preserved …

There is a high prevalence of heart failure (HF) worldwide, which has significant
consequences for healthcare costs, patient death and quality of life. Therefore, there has …

Purpose This study aimed to investigate the potential diagnostic value of miR‐214, B‐type
natriuretic peptide (BNP), N terminal‐pro BNP (NT‐proBNP) and soluble ST2 (sST2) in …