Colorectal cancer (CRC) is one of the most frequently diagnosed tumor in humans and one
of the most common causes of cancer-related death worldwide. The pathogenesis of CRC …

The tripartite motif (TRIM) family proteins play a great role in carcinogenesis. However, the
expression pattern, prognostic value and biological functions of tripartite motif containing 23 …

Cancer is the second leading cause of human death across the world. Tripartite motif (TRIM)
family, with E3 ubiquitin ligase activities in majority of its members, is reported to be involved …

Colorectal cancer (CRC) represents one of the most widespread forms of cancer in the
population and, as all malignant tumors, often develops resistance to chemotherapies with …

Abstract Tripartite motif-containing 59 (TRIM59) belongs to the tripartite motif (TRIM) protein
family and is upregulated in various malignancies. However, its expression in colorectal …

New clinical evidence suggests that dysregulation of the ubiquitin-mediated destruction of
tumor suppressors or oncogene products is probably engaged in the etiology of leukemia …

The aim of the present study was to clarify the clinical implication and functional role of
tripartite motif-59 (TRIM59) in colorectal carcinoma (CRC) and explore the underlying …

Background The tripartite motif (TRIM) family proteins are implicated in the pathogenesis of
various human malignancies. The up-regulation and oncogenic roles of TRIM52 have been …

The tripartite motif (TRIM) protein family is attracting increasing interest in oncology. As a
protein family based on structure rather than function, a plethora of biological activities are …

Tripartite motif containing 25 (TRIM25) is a member of TRIM proteins and functions as an E3
(ubiquitin ligase). It has been found to act as an oncogene in gastric cancer cells and is …