Apolipoproteins in vascular biology and atherosclerotic disease

A Mehta, MD Shapiro - Nature Reviews Cardiology, 2022 - nature.com
Apolipoproteins are important structural components of plasma lipoproteins that influence
vascular biology and atherosclerotic disease pathophysiology by regulating lipoprotein …

[HTML][HTML] The functional role of lipoproteins in atherosclerosis: novel directions for diagnosis and targeting therapy

Y Lu, X Cui, L Zhang, X Wang, Y Xu, Z Qin… - Aging and …, 2022 - ncbi.nlm.nih.gov
Dyslipidemia, characterized by a high level of lipids (cholesterol, triglycerides, or both), can
increase the risk of developing and progressing atherosclerosis. As atherosclerosis …

Apolipoprotein B and cardiovascular disease: biomarker and potential therapeutic target

J Behbodikhah, S Ahmed, A Elyasi, LJ Kasselman… - Metabolites, 2021 - mdpi.com
Apolipoprotein (apo) B, the critical structural protein of the atherogenic lipoproteins, has two
major isoforms: apoB48 and apoB100. ApoB48 is found in chylomicrons and chylomicron …

Apolipoprotein B, the major protein component of triglyceride-rich and low density lipoproteins.

L Chan - 1992 - cabidigitallibrary.org
A review. Apolipoprotein (apo) B-100 is a major component of very low density lipoproteins
(VLDL), intermediate density lipoprotein (LDL), low density lipoprotein (LDL), and a unique …

Apolipoproteins AI and B: biosynthesis, role in the development of atherosclerosis and targets for intervention against cardiovascular disease

SO Olofsson, O Wiklund, J Borén - Vascular health and risk …, 2007 - Taylor & Francis
Apolipoprotein (apo) AI and apoB are the major apolipoproteins of high-density lipoprotein
(HDL) and low-density lipoprotein (LDL), respectively. ApoB assembles the precursor of …

Apolipoprotein B: a clinically important apolipoprotein which assembles atherogenic lipoproteins and promotes the development of atherosclerosis

SO Olofsson, J Boren - Journal of internal medicine, 2005 - Wiley Online Library
Apolipoprotein (apo) B exists in two forms apoB100 and apoB48. ApoB100 is present on
very low‐density lipoproteins (VLDL), intermediate density lipoproteins (IDL) and LDL …

High-density lipoproteins and atherosclerosis

DJ Rader - The American journal of cardiology, 2002 - Elsevier
High-density lipoproteins (HDLs) are strongly related to risk of atherosclerotic cardiovascular
disease. Low levels of HDL cholesterol are a major cardiovascular risk factor, and …

Recent progress in understanding apolipoprotein B.

SG Young - Circulation, 1990 - Am Heart Assoc
For the past 5 years, investigators from many different laboratories have contributed to a
greatly increased understanding of two very important lipid-carrying proteins in plasma--apo …

Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …

G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …

Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.

MM Véniant, V Pierotti, D Newland… - The Journal of …, 1997 - Am Soc Clin Investig
All classes of lipoproteins considered to be atherogenic contain apo-B100 or apo-B48.
However, there is a distinct paucity of data regarding whether lipoproteins containing apo …