Seeing the Future: A Review of Ocular Therapy

M Whalen, M Akula, SM McNamee, MM DeAngelis… - Bioengineering, 2024 - mdpi.com
Ocular diseases present a unique challenge and opportunity for therapeutic development.
The eye has distinct advantages as a therapy target given its accessibility …

Delivery strategies for treatment of age-related ocular diseases: From a biological understanding to biomaterial solutions

V Delplace, S Payne, M Shoichet - Journal of Controlled Release, 2015 - Elsevier
Age-related ocular diseases, such as age-related macular degeneration (AMD), diabetic
retinopathy, and glaucoma, result in life-long functional deficits and enormous global health …

Recent advances of ocular drug delivery systems: prominence of ocular implants for chronic eye diseases

M Mostafa, A Al Fatease, RG Alany, H Abdelkader - Pharmaceutics, 2023 - mdpi.com
Chronic ocular diseases can seriously impact the eyes and could potentially result in
blindness or serious vision loss. According to the most recent data from the WHO, there are …

[HTML][HTML] Recent Strategies for Ocular Drug Delivery: Promises and Challenges

AH El-Kamel, AA Ashour - Advanced Drug Delivery Systems, 2022 - intechopen.com
Ocular diseases include various anterior and posterior segment diseases. Due to the unique
anatomy and physiology of the eye, efficient ocular drug delivery is a great challenge to …

Nanotechnology and drug delivery

UB Kompella - J Ocul Pharmacol Ther, 2013 - academia.edu
Adequate and persistent drug delivery to the target tissues is a key bottleneck in drug
development for eye diseases. Additionally, early diagnosis of eye diseases and …

[HTML][HTML] Advanced drug delivery and targeting technologies for the ocular diseases

J Barar, A Aghanejad, M Fathi, Y Omidi - BioImpacts: BI, 2016 - ncbi.nlm.nih.gov
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Introduction: Ocular targeted therapy has enormously been advanced by implementation of …

Nanostructures Overcoming the Ocular Barrier: Drug Delivery Strategies

A Urtti - 2012 - books.rsc.org
Various cellular and tissue targets in ocular drug treatment have distinct challenges of drug
delivery. Anterior targets are involved in the treatment of infections, inflammatory conditions …

Ocular drug delivery: molecules, cells, and genes

X Liu, CR Brandt, CA Rasmussen… - Canadian journal of …, 2007 - Elsevier
Recent advances in molecular cell biology have led to the exploration of new therapies
based on molecules, cells, and genes to treat a variety of ocular disorders. In this review, we …

Biomaterial Drug Delivery Systems for Prominent Ocular Diseases

A Sapowadia, D Ghanbariamin, L Zhou, Q Zhou… - Pharmaceutics, 2023 - mdpi.com
Ocular diseases, such as age-related macular degeneration (AMD) and glaucoma, have
had a profound impact on millions of patients. In the past couple of decades, these diseases …

Overview of Recent Advances in Nano-Based Ocular Drug Delivery

LC Liu, YH Chen, DW Lu - International Journal of Molecular Sciences, 2023 - mdpi.com
Ocular diseases profoundly impact patients' vision and overall quality of life globally.
However, effective ocular drug delivery presents formidable challenges within clinical …