Statistical analysis plan for the Sleep Apnea cardioVascular Endpoints study: An
international randomised controlled trial to determine whether continuous positive airways …

Rationale Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular
disease. Continuous positive airway pressure (CPAP) delivered via a nasal mask during …

Abstract The Sleep Apnea cardioVascular Endpoints (SAVE) study is an ongoing
investigator-initiated and conducted, international, multicenter, open, blinded endpoint …

Objective: There is uncertainty over whether treatment of obstructive sleep apnea (OSA) can
prevent serious cardiovascular (CV) events. Design and Method: SAVE (NCT00738179; …

Obstructive sleep apnea is a common disorder with increased risk for cardiovascular
morbidity and mortality. The first choice of treatment of obstructive sleep apnea is continuous …

The sleep apnea cardiovascular endpoints (SAVE) study (Clinical Trials Registration
Number: NCT00738170) is an academic initiated and conducted, multinational, open …

Background: Obstructive sleep apnea (OSA) is a risk factor for cardiovascular death in men,
but whether it is also a risk factor in women is unknown. Objective: To investigate whether …

Obstructive sleep apnea (OSA) is a common condition in patients with cardiovascular
diseases (CVD). The first line treatment of OSA is continuous positive airway pressure …

Prospective studies show an association between obstructive sleep apnea and
cardiovascular disease. Continuous positive airway pressure (CPAP) is the treatment of …

Obstructive sleep apnea is common, underdiagnosed, undertreated, and highly associated
with cardiovascular risk. It is characterized by daytime sleepiness and disrupted sleep and is …