Effects of maternal obesity and gestational diabetes mellitus on the placenta: current knowledge and targets for therapeutic interventions

S Bedell, J Hutson, B de Vrijer… - Current vascular …, 2021 - ingentaconnect.com
Obesity and gestational diabetes mellitus (GDM) are becoming more common among
pregnant women worldwide and are individually associated with a number of placenta …

Effects of maternal obesity on placental phenotype

AL Fowden, EJ Camm… - Current Vascular …, 2021 - ingentaconnect.com
The incidence of obesity is rising rapidly worldwide with the consequence that more women
are entering pregnancy overweight or obese. This leads to an increased incidence of clinical …

Placental transport and metabolism of energy substrates in maternal obesity and diabetes

LA Gallo, HL Barrett, MD Nitert - Placenta, 2017 - Elsevier
Maternal obesity is growing in prevalence and is associated with increased morbidity and
mortality for both mother and child. Women who are obese during pregnancy have a greater …

[HTML][HTML] Effects of maternal obesity on placental function and fetal development

KR Howell, TL Powell - Reproduction (Cambridge, England), 2017 - ncbi.nlm.nih.gov
Obesity has reached epidemic proportions and pregnancies in obese mothers have
increased risk for complications including gestational diabetes, hypertensive disorders …

Placental function in maternal obesity

AC Kelly, TL Powell, T Jansson - Clinical Science, 2020 - portlandpress.com
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …

Obesity and gestational diabetes independently and collectively induce specific effects on placental structure, inflammation and endocrine function in a cohort of South …

E Musa, E Salazar‐Petres, A Arowolo… - The Journal of …, 2023 - Wiley Online Library
Maternal obesity and gestational diabetes mellitus (GDM) are associated with insulin
resistance and health risks for mother and offspring. Obesity is also characterized by low …

[HTML][HTML] Fetoplacental endothelial dysfunction in gestational diabetes mellitus and maternal obesity: A potential threat for programming cardiovascular disease

MS Diniz, U Hiden, I Falcão-Pires, PJ Oliveira… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Gestational diabetes mellitus (GDM) and maternal obesity (MO) increase the risk of adverse
fetal outcomes, and the incidence of cardiovascular disease later in life. Extensive research …

Obesity and the placenta: a consideration of nutrient exchange mechanisms in relation to aberrant fetal growth

L Higgins, SL Greenwood, M Wareing, CP Sibley… - Placenta, 2011 - Elsevier
The obesity epidemic, including childhood obesity, is rapidly gaining strength as one of the
most significant challenges to the health of the global community in the 21st Century. The …

Maternal obesity influences placental nutrient transport, inflammatory status, and morphology in human term placenta

P Nogues, E Dos Santos… - The Journal of …, 2021 - academic.oup.com
Context Maternal obesity has a significant impact on placental development. However, this
impact on the placenta's structure and function (ie, nutrient transport and hormone and …

Mechanisms of endothelial dysfunction in pre-eclampsia and gestational diabetes mellitus: windows into future cardiometabolic health?

CJ McElwain, E Tuboly, FP McCarthy… - Frontiers in …, 2020 - frontiersin.org
Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …