Oxidative stress: The core pathogenesis and mechanism of Alzheimer's disease
As the number of patients with Alzheimer's disease (AD) increases, it brings great suffering
to their families and causes a heavy socioeconomic burden to society. A vast amount of …
to their families and causes a heavy socioeconomic burden to society. A vast amount of …
Oxidative stress in Alzheimer's disease
Z Chen, C Zhong - Neuroscience bulletin, 2014 - Springer
Oxidative stress plays a significant role in the pathogenesis of Alzheimer's disease (AD), a
devastating disease of the elderly. The brain is more vulnerable than other organs to …
devastating disease of the elderly. The brain is more vulnerable than other organs to …
Oxidative stress and the pathogenesis of Alzheimer′ s disease
Y Zhao, B Zhao - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …
Alzheimer's disease: redox dysregulation as a common denominator for diverse pathogenic mechanisms
R Von Bernhardi, J Eugenín - Antioxidants & redox signaling, 2012 - liebertpub.com
Alzheimer's disease (AD) is the most common cause of dementia and a progressive
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …
Oxidative stress in Alzheimer's disease
V Chauhan, A Chauhan - Pathophysiology, 2006 - Elsevier
Oxidative damage is a major feature in the pathophysiology of Alzheimer's disease (AD). In
this review, we discuss free radical-mediated damage to the biochemical components …
this review, we discuss free radical-mediated damage to the biochemical components …
Oxidative stress in Alzheimer's disease: implications for prevention and therapy
C Behl - Alzheimer's Disease: Cellular and Molecular Aspects of …, 2005 - Springer
Oxidative stress is a marker of neurodegeneration and has been recently shown to be also
involved in the early stages of the pathogenesis of various neurodegenerative disorders. In …
involved in the early stages of the pathogenesis of various neurodegenerative disorders. In …
Roles of oxidative stress in synaptic dysfunction and neuronal cell death in Alzheimer's disease
G Plascencia-Villa, G Perry - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a brain disorder that progressively undermines memory and
thinking skills by affecting the hippocampus and entorhinal cortex. The main …
thinking skills by affecting the hippocampus and entorhinal cortex. The main …
Oxidative stress hypothesis in Alzheimer's disease
WR Markesbery - Free radical biology and medicine, 1997 - Elsevier
The major hurdle in understanding Alzheimer's disease (AD) is a lack of knowledge about
the etiology and pathogenesis of selective neuron death. In recent years, considerable data …
the etiology and pathogenesis of selective neuron death. In recent years, considerable data …
Oxidative stress and beta amyloid in Alzheimer's disease. Which comes first: the chicken or the egg?
The pathogenesis of Alzheimer's disease involves β amyloid (Aβ) accumulation known to
induce synaptic dysfunction and neurodegeneration. The brain's vulnerability to oxidative …
induce synaptic dysfunction and neurodegeneration. The brain's vulnerability to oxidative …
Alzheimer disease and oxidative stress
G Perry, AD Cash, MA Smith - BioMed Research International, 2002 - Wiley Online Library
Research in Alzheimer disease has recently demonstrated compelling evidence on the
importance of oxidative processes in its pathogenesis. Cellular changes show that oxidative …
importance of oxidative processes in its pathogenesis. Cellular changes show that oxidative …