In Silico Bioinformatics Analysis on the Role of Long Non-Coding RNAs as Drivers and Gatekeepers of Androgen-Independent Prostate Cancer Using LNCaP and PC …

M Mbeje, J Kandhavelu, C Penny… - Current Issues in …, 2023 - mdpi.com
Prostate cancer (PCa) is the leading cancer in men globally. The association between PCa
and long non-coding RNAs (lncRNAs) has been reported. Aberrantly expressed lncRNAs …

[HTML][HTML] Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of prostate cancer

M Taheri, E Badrlou, BM Hussen, AH Kashi… - Frontiers in …, 2023 - frontiersin.org
Long non-coding RNAs (lncRNAs) are regulatory transcripts with essential roles in the
pathogenesis of almost all types of cancers, including prostate cancer. They can act as …

[HTML][HTML] LncRNAs and miRNAs: potential biomarkers and therapeutic targets for prostate cancer

G Ma, M Tang, Y Wu, X Xu, F Pan… - American journal of …, 2016 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is the second lethal disease for men in western countries. Although
androgen receptor (AR) signaling has been widely investigated, noncoding RNAs …

Updated Review on Analysis of long Non-coding RNAs as Emerging Diagnostic and Therapeutic Targets in Prostate Cancers

Z Ke, X Hu, Y Liu, D Shen, MI Khan, J Xiao - Critical Reviews in Oncology …, 2024 - Elsevier
Despite advancements, prostate cancers (PCa) are a significant global health due to
delayed diagnosis and therapeutic resistance. This review delves into the complex …

Current insights into long non-coding RNAs (LncRNAs) in prostate cancer

MA Smolle, T Bauernhofer, K Pummer… - International journal of …, 2017 - mdpi.com
The importance of long non-coding RNAs (lncRNAs) in the pathogenesis of various
malignancies has been uncovered over the last few years. Their dysregulation often …

Linc00963: a novel, long non-coding RNA involved in the transition of prostate cancer from androgen-dependence to androgen-independence

L Wang, S Han, G Jin, X Zhou, M Li… - International …, 2014 - spandidos-publications.com
Whole genome transcriptomic analyses have identified a large number of long non-coding
RNAs (lncRNAs), many of which are involved in a variety of biological functions. However …

A thorough understanding of the role of lncRNA in prostate cancer pathogenesis; Current knowledge and future research directions

R Haghighi, RY Castillo-Acobo, AH Amin… - … -Research and Practice, 2023 - Elsevier
In the entire world, prostate cancer (PCa) is one of the most common and deadly cancers.
Treatment failure is still common among patients, despite PCa diagnosis and treatment …

[HTML][HTML] Identification of androgen-responsive lncRNAs as diagnostic and prognostic markers for prostate cancer

X Wan, W Huang, S Yang, Y Zhang, H Pu, F Fu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is a leading cause of mortality among males. Long non-coding RNAs
(lncRNAs) are subclass of noncoding RNAs that may act as biomarkers and therapeutic …

Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention

S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

The emerging role of noncoding RNA in prostate cancer progression and its implication on diagnosis and treatment

K Takayama, S Inoue - Briefings in functional genomics, 2016 - academic.oup.com
Recent transcriptome studies using next-generation sequencing have detected aberrant
changes in the expression of noncoding RNAs (ncRNAs) associated with cancer. For …