Glycan Mapping of Low-Molecular-Weight Heparin Using Mass Spectral Correction Based on Chromatography Fitting with “Glycomapping” Software
N Yan, F Song, Y Ouyang, D Li, H Tian, L Yi… - Analytical …, 2022 - ACS Publications
In this work, the first version of “Glycomapping” software is developed for the analysis of the
most common low-molecular-weight heparin (LMWH), enoxaparin. Using ultrahigh …
most common low-molecular-weight heparin (LMWH), enoxaparin. Using ultrahigh …
Mapping of low molecular weight heparins using reversed phase ion pair liquid chromatography–mass spectrometry
D Li, L Chi, L Jin, X Xu, X Du, S Ji, L Chi - Carbohydrate polymers, 2014 - Elsevier
Low molecular weight heparins (LMWHs) are structurally complex, highly sulfated and
negatively charged, linear carbohydrate polymers prepared by chemical or enzymatic …
negatively charged, linear carbohydrate polymers prepared by chemical or enzymatic …
Fragment profiling of low molecular weight heparins using reversed phase ion pair liquid chromatography-electrospray mass spectrometry
X Xu, D Li, L Chi, X Du, X Bai, L Chi - Carbohydrate research, 2015 - Elsevier
Low molecular weight heparins (LMWHs) are linear and highly charged carbohydrate
polymers prepared by chemical or enzymatic depolymerization of heparin. Compared to …
polymers prepared by chemical or enzymatic depolymerization of heparin. Compared to …
Molecular weight determination of hyaluronic acid by gel filtration chromatography coupled to matrix-assisted laser desorption ionization mass spectrometry
B Yeung, D Marecak - Journal of Chromatography A, 1999 - Elsevier
An analytical approach has been described for the molecular weight characterization of
enzymatically degraded hyaluronic acid (HA). The approach involved the combined use of …
enzymatically degraded hyaluronic acid (HA). The approach involved the combined use of …
Software tool for the structural determination of glycosaminoglycans by mass spectrometry
Structural elucidation of glycosaminoglycans (GAGs) is one of the major challenges in
biochemical analysis. This is mainly because of the diversity of GAG sulfation and N …
biochemical analysis. This is mainly because of the diversity of GAG sulfation and N …
Preparation and characterization of heparin hexasaccharide library with N-unsubstituted glucosamine residues
QT Liang, JY Du, Q Fu, JH Lin, Z Wei - Glycoconjugate journal, 2015 - Springer
The rare N-unsubstituted glucosamine (GlcNH 3+) residues in heparan sulfate (HS) have
important biological and pathophysiological roles. Therefore, the ability to chemically …
important biological and pathophysiological roles. Therefore, the ability to chemically …
HepParser: an intelligent software program for deciphering low-molecular-weight heparin based on mass spectrometry
H Wang, Y Wang, M Hou, C Zhang, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Low-molecular-weight heparins (LMWHs) are considered to be the most successful
carbohydrate-based drugs because of their wide use as anticoagulants in clinics. The …
carbohydrate-based drugs because of their wide use as anticoagulants in clinics. The …
GAG-ID: Heparan Sulfate (HS) and Heparin Glycosaminoglycan High-Throughput Identification Software*[S]
Heparin and heparan sulfate are very large linear polysaccharides that undergo a complex
variety of modifications and are known to play important roles in human development, cell …
variety of modifications and are known to play important roles in human development, cell …
Towards GAG glycomics: analysis of highly sulfated heparins by MALDI-TOF mass spectrometry
Glycomics is a developing field that provides structural information on complex populations
of glycans isolated from tissues, cells and organs. Strategies employing matrix-assisted …
of glycans isolated from tissues, cells and organs. Strategies employing matrix-assisted …
GlycCompSoft: software for automated comparison of low molecular weight heparins using top-down LC/MS data
Low molecular weight heparins are complex polycomponent drugs that have recently
become amenable to top-down analysis using liquid chromatography-mass spectrometry …
become amenable to top-down analysis using liquid chromatography-mass spectrometry …