In this work, the first version of “Glycomapping” software is developed for the analysis of the
most common low-molecular-weight heparin (LMWH), enoxaparin. Using ultrahigh …

Low molecular weight heparins (LMWHs) are structurally complex, highly sulfated and
negatively charged, linear carbohydrate polymers prepared by chemical or enzymatic …

Low molecular weight heparins (LMWHs) are linear and highly charged carbohydrate
polymers prepared by chemical or enzymatic depolymerization of heparin. Compared to …

An analytical approach has been described for the molecular weight characterization of
enzymatically degraded hyaluronic acid (HA). The approach involved the combined use of …

Structural elucidation of glycosaminoglycans (GAGs) is one of the major challenges in
biochemical analysis. This is mainly because of the diversity of GAG sulfation and N …

The rare N-unsubstituted glucosamine (GlcNH 3+) residues in heparan sulfate (HS) have
important biological and pathophysiological roles. Therefore, the ability to chemically …

Low-molecular-weight heparins (LMWHs) are considered to be the most successful
carbohydrate-based drugs because of their wide use as anticoagulants in clinics. The …

Glycomics is a developing field that provides structural information on complex populations
of glycans isolated from tissues, cells and organs. Strategies employing matrix-assisted …

Heparin and heparan sulfate are very large linear polysaccharides that undergo a complex
variety of modifications and are known to play important roles in human development, cell …

Low molecular weight heparins are complex polycomponent drugs that have recently
become amenable to top-down analysis using liquid chromatography-mass spectrometry …