[HTML][HTML] Verteporfin-Loaded Mesoporous Silica Nanoparticles' Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo

N Clemente, I Miletto, E Gianotti, M Sabbatini… - International Journal of …, 2021 - mdpi.com
Photodynamic therapy (PDT) has been pointed out as a candidate for improving melanoma
treatment. Nanotechnology application in PDT has increased its efficacy by reducing side …

[HTML][HTML] Verteporfin-loaded mesoporous silica nanoparticles inhibit mouse melanoma proliferation in vitro and in vivo

N Clemente, I Miletto, E Gianotti, M Invernizzi… - … of Photochemistry and …, 2019 - Elsevier
Melanoma is one of the most lethal tumors among the skin cancers, arising from complex
genetic mutations in melanocyte. Melanoma microenvironment is very heterogeneous …

[HTML][HTML] Verteporfin based silica nanoparticle for in vitro selective inhibition of human highly invasive melanoma cell proliferation

M Rizzi, S Tonello, BM Estevão, E Gianotti… - … of Photochemistry and …, 2017 - Elsevier
Photodinamic therapy (PDT) has gained an increasing interest as a new tool to treat skin
cancers such as melanoma. This clinical approach take advantage from the combination of …

[HTML][HTML] Recent Innovations of Mesoporous Silica Nanoparticles Combined with Photodynamic Therapy for Improving Cancer Treatment

DS Nady, A Hassan, MU Amin, U Bakowsky, SA Fahmy - Pharmaceutics, 2023 - mdpi.com
Cancer is a global health burden and is one of the leading causes of death. Photodynamic
therapy (PDT) is considered an alternative approach to conventional cancer treatment. PDT …

Microneedle-assisted topical delivery of photodynamically active mesoporous formulation for combination therapy of deep-seated melanoma

HP Tham, K Xu, WQ Lim, H Chen, M Zheng… - ACS …, 2018 - ACS Publications
Topical treatment using photodynamic therapy (PDT) for many types of skin cancers has
largely been limited by the inability of existing photosensitizers to penetrate into the deep …

Nano-Photosensitizer Directed Targeted Phototherapy Effective Against Oral Cancer in Animal Model

L Yu, G Zhu, Z Zhang, Z Xu, W Peng… - International Journal …, 2023 - Taylor & Francis
Background Photodynamic therapy (PDT) has emerged as a promising strategy for oral
cancer treatment. Verteporfin is a powerful photosensitizer and widely used in the treatment …

[HTML][HTML] Mesoporous silica coated spicules for photodynamic therapy of metastatic melanoma

X Liang, J Zhang, C Zhang, H Zhai, P Yang… - Journal of …, 2024 - Springer
We report on the fabrication of mesoporous silicon dioxide coated Haliclona sp. spicules
(mSHS) to enhance the delivery of the insoluble photosensitizer protoporphyrin IX (PpIX) …

[HTML][HTML] Mesoporous silica-based nanoplatforms for the delivery of photodynamic therapy agents

S Hong, Y Choi - Journal of pharmaceutical investigation, 2018 - Springer
Photodynamic therapy (PDT) is an established method for the treatment of cancer which
utilizes light, a photosensitizer (PS), and oxygen. Unfavourable characteristics of most PSs …

[HTML][HTML] Curcumin-loaded PEGylated mesoporous silica nanoparticles for effective photodynamic therapy

G Kuang, Q Zhang, S He, Y Liu - RSC advances, 2020 - pubs.rsc.org
Curcumin (Cur) can be used as a photosensitizer in the photodynamic therapy (PDT) of
cancer, but its low bioavailability limits further clinical application. A mesoporous silica …

The promotion of human malignant melanoma growth by mesoporous silica nanoparticles through decreased reactive oxygen species

X Huang, J Zhuang, X Teng, L Li, D Chen, X Yan… - Biomaterials, 2010 - Elsevier
The concept that mesoporous silica nanoparticles (MSNs) are regarded as ideal novel drug
delivery carriers in tumor therapy has been introduced extensively, but the effects of MSNs …