Background & Aims The etiology of abdominal pain in postinfectious, diarrhea-predominant
irritable bowel syndrome (PI-IBS-D) is unknown, and few treatment options exist. Catechol-O …

Inflammatory bowel diseases (IBDs), such as Crohn's disease and Q8 ulcerative colitis, are
characterized by chronic Q9 intestinal inflammation associated with abdominal pain …

Background & Aims The abdominal discomfort experienced by patients with colitis may be
attributable in part to the presence of small intestinal dysmotility, yet mechanisms linking …

Background & Aims Despite achieving endoscopic remission, more than 20% of
inflammatory bowel disease patients experience chronic abdominal pain. These patients …

Background Chronic visceral pain is a defining feature of irritable bowel syndrome (IBS). IBS
patients often show alterations in innate and adaptive immune function which may contribute …

Methods We established the IBS-D rat model and evaluated it using the nociceptive visceral
hypersensitivity test, myeloperoxidase activity assay, restraint stress-induced defecation …

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is characterized by
chronic abdominal pain concurrent with altered bowel habit. Polyunsaturated fatty acid …

Irritable bowel syndrome (IBS) displays chronic abdominal pain with altered defecation.
Most of the patients develop visceral hypersensitivity possibly resulting from impaired gut …

Background Inflammatory Bowel Disease (IBD) is characterized by overt inflammation of the
intestine and is typically accompanied by symptoms of bloody diarrhea, abdominal pain and …

Inflammatory bowel disease (IBD), comprising Crohn's disease and Ulcerative colitis, is a
relapsing and remitting disease of the gastrointestinal tract, presenting with chronic …