The striatum integrates inputs from the cortex and thalamus, which display concomitant or
sequential activity. The striatum assists in forming memory, with acquisition of the behavioral …

The striatum is the major input nucleus of basal ganglia, an ensemble of interconnected sub-
cortical nuclei associated with fundamental processes of action-selection and procedural …

The basal ganglia is a brain region critically involved in reinforcement learning and motor
control. Synaptic plasticity in the striatum of the basal ganglia is a cellular mechanism …

Corticostriatal projections constitute the main input to the basal ganglia, an ensemble of
interconnected subcortical nuclei involved in procedural learning. Thus, long‐term plasticity …

The striatum mediates two learning modalities: goal-directed behavior in dorsomedial (DMS)
and habits in dorsolateral (DLS) striata. The synaptic bases of these learnings are still …

Corticostriatal projections originate from the entire cerebral cortex and provide the major
source of glutamatergic inputs to the basal ganglia. Despite the importance of corticostriatal …

Activity-dependent long-term potentiation (LTP) and depression (LTD) of synaptic strength
underlie multiple forms of learning and memory. Spike-timing-dependent plasticity (STDP) …

Plasticity at synapses between the cortex and striatum is considered critical for learning
novel actions. However, investigations of spike-timing-dependent plasticity (STDP) at these …

Highlights•Hebbian protocols induce bidirectional plasticity (LTP and LTD) in the
striatum.•Multiple pathways interact to induce activity-dependent STDP in the …

Basal ganglia, an ensemble of interconnected subcortical nuclei, are involved in adaptive
motor planning and procedural learning. Striatum, the primary input nucleus of basal …