Background Patients with multiple sclerosis (MS) have significantly lower vitamin D levels.
Cholesterol is known to be the precursor for vitamin D synthesis, and cholesterol removal is …

Stroke is a serious complication associated with hypertension. Because cytochrome P450
1A1 (CYP1A1) is involved in the production of arachidonic acid-derived vasoactive …

The human cytochrome P450 (CYP) superfamily includes at least 57 genes that encode
enzymes with diverse metabolic and biosynthetic functions. This study was conducted in …

Excess cholesterol is removed from the brain via hydroxylation mediated by cholesterol 24S-
hydroxylase (CYP46), which is a mechanism of maintaining cholesterol homeostasis in the …

Background The single-nucleotide polymorphism (SNP) rs11191548, near the CYP17A1
gene, has been identified as being associated with hypertension and systolic blood …

Abstract Background Cytochrome P450 (CYPs) participate in the mechanisms of
cardiovascular disease. The purpose of this research was to evaluate the contributions of …

Background CYP17A1 gene encodes P450c17 proteins, which is a key enzyme that
catalyzes the formation of sex hormones. Many clinical studies showed that sex hormones …

Objective To assess the association of genetic polymorphisms of CYP2C19* 2,* 3,* 17 with
the recurrence risk of ischemic stroke during clopidogrel prevention in ethnic Han Chinese …

Abstract Cytochrome P450 1A1 (CYP1A1) is involved in the production of arachidonic acid-
derived vasoactive substance. We hypothesized that CYP1A1 polymorphism might be …

Whether the variations in the cholesterol 24S-hydroxylase (CYP46A1) gene would raise
Alzheimer's risk is still undetermined. A previous meta-analysis about the association …