CYP genetic variants, CYP metabolite levels, and symptomatic carotid stenosis in ischemic stroke patients
X Yi, D Liao, L Wu, H Chen, J Li… - Journal of atherosclerosis …, 2016 - jstage.jst.go.jp
Aim: To evaluate the relationship between CYP genetic polymorphisms and CYP metabolite
levels with carotid artery stenosis in acute ischemic stroke (IS) patients. Methods: Eleven …
levels with carotid artery stenosis in acute ischemic stroke (IS) patients. Methods: Eleven …
A functional polymorphism in the CYP3A4 gene is associated with increased risk of coronary heart disease in the Chinese Han population
B He, L Shi, J Qiu, L Tao, R Li, L Yang… - Basic & clinical …, 2011 - Wiley Online Library
CYP3A4 is a major member of the cytochrome P450 (CYP) enzymes which play crucial roles
in cardiovascular diseases. Recently, a novel polymorphism in the CYP3A4 gene, IVS10+ …
in cardiovascular diseases. Recently, a novel polymorphism in the CYP3A4 gene, IVS10+ …
Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on 5021 …
B Hou, X Jia, Z Deng, X Liu, H Liu, H Yu, S Liu - Human Genomics, 2020 - Springer
Background Several genome-wide association studies have identified single-nucleotide
polymorphisms (SNPs), such as rs4409766, rs1004467, and rs3824755 in CYP17A1 and …
polymorphisms (SNPs), such as rs4409766, rs1004467, and rs3824755 in CYP17A1 and …
Association of genetic polymorphisms of CYP 2C19 with hypertension in a Chinese Han population
Y Ma, W Ni, W Zhu, Y Xiong, X Deng - Blood pressure, 2011 - Taylor & Francis
Abstract Objectives. Cytochrome P450 (CYP) 2C19 is expressed in vascular endothelium
and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs) …
and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs) …
Polymorphisms in CYP450 genes and the therapeutic effect of atorvastatin on ischemic stroke: a retrospective cohort study in Chinese population
C Peng, Y Ding, X Yi, Y Shen, Z Dong, L Cao, Q Li… - Clinical Therapeutics, 2018 - Elsevier
Purpose Ischemic stroke (IS) is one of the most common neurologic diseases and is the
main cause of death and disability in the Chinese population. This retrospective cohort study …
main cause of death and disability in the Chinese population. This retrospective cohort study …
Interaction between ALOX5AP and CYP3A5 gene variants significantly increases the risk for cerebral infarctions in Chinese
LF Chi, XY Yi, MJ Shao, J Lin, Q Zhou - Neuroreport, 2014 - journals.lww.com
In this study, we investigated associations between susceptibility genes and cerebral
infarctions in a Chinese population, and whether gene–gene interactions increase the risk of …
infarctions in a Chinese population, and whether gene–gene interactions increase the risk of …
Analysis of CYP3A4 genetic polymorphisms in Han Chinese
Our study aimed to comprehensively investigate the genetic polymorphisms of CYP3A4 in
Han Chinese. We sequenced the gene regions of CYP3A4, including its promoter, exons …
Han Chinese. We sequenced the gene regions of CYP3A4, including its promoter, exons …
Association between the CYP4A11 T8590C Variant and Essential Hypertension: New Data from Han Chinese and a Meta-Analysis
HC Yan, JH Liu, J Li, BX He, L Yang, J Qiu, L Li… - PLoS …, 2013 - journals.plos.org
Objective CYP4A11 oxidizes endogenous arachidonic acid to 20-hydroxyeicosatetraenoic
acid, a renal vasoconstrictor and natriuretic in humans. Previous studies demonstrated an …
acid, a renal vasoconstrictor and natriuretic in humans. Previous studies demonstrated an …
Association of interaction between smoking and CYP 2C19* 3 polymorphism with coronary artery disease in a Uighur population
YN Yang, XL Wang, YT Ma, X Xie… - Clinical and Applied …, 2010 - journals.sagepub.com
Objectives: Cytochrome P450 (CYP) 2C19 is expressed in vascular endothelium and
metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which …
metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which …
Association of CYP19A1 and CYP1A2 genetic polymorphisms with type 2 diabetes mellitus risk in the Chinese Han population
Y Yang, P Wang - Lipids in Health and Disease, 2020 - Springer
Background Type 2 diabetes mellitus (T2DM), one of the global health issues, is a group of
metabolic diseases and is affected by several genetic loci in the clinical phenotype. This …
metabolic diseases and is affected by several genetic loci in the clinical phenotype. This …