CYP genetic variants, CYP metabolite levels, and neurologic deterioration in acute ischemic stroke in Chinese population

X Yi, J Lin, C Wang, Q Zhou - Journal of Stroke and Cerebrovascular …, 2017 - Elsevier
Background The mechanisms of neurologic deterioration (ND) are not fully understood. The
aim of the present study was to evaluate the relationship between CYP genetic variants and …

[HTML][HTML] Cytochrome P450 family 4 subfamily F member 2 (CYP4F2) rs1558139, rs2108622 polymorphisms and susceptibility to several cardiovascular and …

T Zhang, K Yu, X Li - BMC Cardiovascular Disorders, 2018 - Springer
Background Inconsistent conclusions have been reported for the genetic relationship
between CYP4F2 (Cytochrome P450 Family 4 Subfamily F Member 2) polymorphisms and …

A Novel Polymorphism of the CYP4A11 Gene is Associated With Coronary Artery Disease

Z Fu, Y Ma, X Xie, D Huang, H Yang… - Clinical and Applied …, 2013 - journals.sagepub.com
Background: CYP4A11 (cytochrome P450, family 4, subfamily A, polypeptide 11) converts
arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), which plays a crucial role in …

The association study between CYP20A1, CYP4F2, CYP2D6 gene polymorphisms and coronary heart disease risk in the Han population in southern China

T Liang, A Liang, X Zhang, Q Wang, H Wu, J He… - Genes & Genomics, 2022 - Springer
Background Coronary heart disease (CHD) is a disease that seriously harms human health.
Genetic factors seriously affect the CHD susceptibility. The CYP20A1, CYP4F2 and CYP2D6 …

Haplotype analyses of CYP17A1 genetic polymorphisms and coronary artery disease in a Uygur population

CF Dai, X Xie, YT Ma, YN Yang, XM Li… - Journal of the Renin …, 2015 - journals.sagepub.com
Background: The relationship between CYP17A1 genetic polymorphisms and coronary
artery disease (CAD) remains unclear. The aim of the present study was to assess the …

[HTML][HTML] Effects of CYP3A4 Polymorphisms on Drug Addiction Risk Among the Chinese Han Population

L Wang, M Bai, T Jin, J Zheng, Y Wang, Y He… - Frontiers in Public …, 2019 - frontiersin.org
Background: Cytochrome P450 3A4 (CYP3A4) regulates pharmacokinetic and
pharmacodynamic interactions during the process of drug absorption and metabolism …

[HTML][HTML] Analysis of the CYP2C19 genetic polymorphism in Han and Uyghur patients with cardiovascular and cerebrovascular diseases in the Kashi area of Xinjiang

Y Li, H Yang, X Zou, L Xiong, Z Li, J Luo… - … Medical Journal of …, 2014 - ncbi.nlm.nih.gov
Analysis of the CYP2C19 Genetic Polymorphism in Han and Uyghur Patients with Cardiovascular
and Cerebrovascular Diseases in the Kashi Area of Xinjiang - PMC Back to Top Skip to main …

CYP7A1 Gene Polymorphism Located in the 5′ Upstream Region Modifies the Risk of Coronary Artery Disease

T Iwanicki, A Balcerzyk, P Niemiec, T Nowak… - Disease …, 2015 - Wiley Online Library
Background. 7‐Alpha cholesterol hydroxylase (CYP7A1), the first enzyme of classic
conversion pathway leading from cholesterol to bile acids synthesis, is encoded by CYP7A1 …

Impact of interaction between CYP1A1 genetic polymorphisms and smoking on coronary artery disease in the Han of China

DD Peng, W Xie, ZX Yu - Clinical and Experimental Hypertension, 2017 - Taylor & Francis
Aims: To investigate the association of CYP1A1 genotype and additional gene–smoking
interaction with coronary artery disease (CAD) risk based on a Chinese case-control study …

[HTML][HTML] A common polymorphism of CYP4A11 is associated with blood pressure in a Chinese population

R Zhang, J Lu, C Hu, C Wang, W Yu, X Ma… - Hypertension …, 2011 - nature.com
Variants of the human CYP4A11, which belongs to the cytochrome P450, family 4, have
been reported to be associated with hypertension in general populations. However, data in …