Objective CYP4A11 oxidizes endogenous arachidonic acid to 20-hydroxyeicosatetraenoic
acid, a renal vasoconstrictor and natriuretic in humans. Previous studies demonstrated an …

Background T8590C polymorphism of CYP4A11 has been associated with hypertension,
though with conflicting results. The aim of this study was to quantitatively summarize the …

CYP4A11 oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid, a metabolite with
renovascular and tubular function in humans. A previous study demonstrated a significant …

Background: CYP4A11 is a member of the cytochrome P450 enzymes and is responsible for
metabolizing arachidonic acid to 20-hydroxyeicosatetraenoic acid, a metabolite involved in …

Variants of the human CYP4A11, which belongs to the cytochrome P450, family 4, have
been reported to be associated with hypertension in general populations. However, data in …

The cytochrome P450 family 3 subfamily A polypeptide 5 (CYP3A5) gene has been
implicated in the regulation of blood pressure (BP) and thus, may serve as a potential risk …

Background: The association of CYP3A5 gene polymorphisms with hypertension in the
Chinese population is unknown. We explored the association between the CYP3A5 …

Using a case–control design, we assessed the association between single nucleotide
polymorphisms of CYP3A4 gene rs4646437 polymorphism and the risk of hypertension in …

Objective CYP4A11, a member of the cytochrome P450 family, acts mainly as an enzyme
that converts arachidonic acid to 20-hydroxyeicosatetraenoic acid, a metabolite involved in …

Background: Hypertension is one of the leading causes of human death and disability.
CYP24A1 regulates vitamin D activity and is closely linked to hypertension. However, the …