Structure–activity relationship and therapeutic benefits of flavonoids in the management of diabetes and associated disorders

S Lodhi, ML Kori - Pharmaceutical Chemistry Journal, 2021 - Springer
Commonly flavonoids are the natural components found in vegetables, spices and colored
fruits. Flavonoids include a large group of polyphenolic compounds, namely flavones …

Higher habitual intakes of flavonoids and flavonoid-rich foods are associated with a lower incidence of type 2 diabetes in the UK Biobank cohort

AS Thompson, A Jennings, NP Bondonno… - Nutrition & …, 2024 - nature.com
Aim To examine the associations of a diet high in flavonoid-rich foods, as reflected by a
“Flavodiet Score”(FDS), the major individual food contributors to flavonoid intake, and …

Exploration of natural flavones' bioactivity and bioavailability in chronic inflammation induced-type-2 diabetes mellitus

L Miao, C Liu, MS Cheong, R Zhong, Y Tan… - Critical Reviews in …, 2023 - Taylor & Francis
Diabetes, being the most widespread illness, poses a serious threat to global public health.
It seems that inflammation plays a critical role in the pathophysiology of diabetes. This …

[HTML][HTML] Role of various flavonoids: Hypotheses on novel approach to treat diabetes

S Mohan, L Nandhakumar - Journal of Medical Hypotheses and Ideas, 2014 - Elsevier
Basically flavonoids are naturally occurring phenolic compounds that are distributed in
plants. They contain wide range of biological activity and lot of research has been carried …

Dietary polyphenols and type 2 diabetes: Human Study and Clinical Trial

H Cao, J Ou, L Chen, Y Zhang… - Critical reviews in …, 2019 - Taylor & Francis
Significant evidence from epidemiological investigations showed that dietary polyphenols
might manage and prevent type 2 diabetes (T2D). This review summarizes human studies …

Flavonoids and type 2 diabetes: Evidence of efficacy in clinical and animal studies and delivery strategies to enhance their therapeutic efficacy

T Hussain, B Tan, G Murtaza, G Liu, N Rahu… - Pharmacological …, 2020 - Elsevier
Diabetes mellitus type 2 (T2DM) is a metabolic disorder develops due to the overproduction
of free radicals where oxidative stress could contribute it. Possible factors are defective …

[HTML][HTML] Flavonoid-rich beverage effects on lipid profile and blood pressure in diabetic patients

R Amani, S Moazen, H Shahbazian… - World journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To compare freeze-dried strawberry (FDS) beverage and strawberry-flavored drink
effects on lipid profile and blood pressure in type 2 diabetic (T2D) patients. METHODS: In a …

Flavonoids as antidiabetic agents

Y Cahyana, T Adiyanti - Indonesian Journal of Chemistry, 2021 - journal.ugm.ac.id
Flavonoids are polyphenol compounds that exert many potential health benefits, including
diabetes type-II, which is the third most common disease that causes death, right after …

Flavonoids and their metabolites: prevention in cardiovascular diseases and diabetes

K Zeka, K Ruparelia, RRJ Arroo, R Budriesi, M Micucci - Diseases, 2017 - mdpi.com
The occurrence of atherosclerosis and diabetes is expanding rapidly worldwide. These two
metabolic disorders often co-occur, and are part of what is often referred to as the metabolic …

Efficacy of flavonoids-containing supplements on insulin resistance and associated metabolic risk factors in overweight and obese subjects: a systematic review and …

J Yao, Y Zhang, J Zhao, XZ Wang, YP Lin… - Frontiers in …, 2022 - frontiersin.org
Background Obesity is becoming a global epidemic. Flavonoids, with anti-inflammatory and
antioxidative functions, are proposed to treat insulin resistance (IR) in obese subjects. We …