Hepatitis C virus and the host: a mutual endurance leaving indelible scars in the host's immunity

MU Mondelli, S Ottolini, B Oliviero, S Mantovani… - International Journal of …, 2023 - mdpi.com
Hepatitis C virus (HCV) has spread worldwide, and it is responsible for potentially severe
chronic liver disease and primary liver cancer. Chronic infection remains for life if not …

Suppression of Innate Immunity by the Hepatitis C Virus (HCV): Revisiting the Specificity of Host–Virus Interactive Pathways

S Barik - International Journal of Molecular Sciences, 2023 - mdpi.com
The hepatitis C virus (HCV) is a major causative agent of hepatitis that may also lead to liver
cancer and lymphomas. Chronic hepatitis C affects an estimated 2.4 million people in the …

Hepatitis C virus (HCV) employs multiple strategies to subvert the host innate antiviral response

JG Bode, ED Brenndörfer, D Häussinger - 2008 - degruyter.com
Hepatitis C virus (HCV) is a serious global health problem which accounts for approximately
40% of chronic liver diseases worldwide. HCV frequently establishes a persistent infection …

Activation and evasion of antiviral innate immunity by hepatitis C virus

SM Horner - Journal of molecular biology, 2014 - Elsevier
Hepatitis C virus (HCV) chronically infects 130–170 million people worldwide and is a major
public health burden. HCV is an RNA virus that infects hepatocytes within liver, and this …

The hepatitis C virus persistence: how to evade the immune system?

N Pavio, MMC Lai - Journal of biosciences, 2003 - Springer
Hepatitis C virus (HCV) is an emerging virus of medical importance. A majority of HCV
infections become chronic and lead to chronic hepatitis, liver cirrhosis and hepatocellular …

Hepatitis C virus: evading the intracellular innate immunity

AR Ferreira, B Ramos, A Nunes, D Ribeiro - Journal of clinical medicine, 2020 - mdpi.com
Hepatitis C virus (HCV) infections constitute a major public health problem and are the main
cause of chronic hepatitis and liver disease worldwide. The existing drugs, while effective …

Hepatitis C virus infection: virus/host interactions

JM Pawlotsky - Journal of viral hepatitis, 1998 - Wiley Online Library
Infection with the hepatitis C virus (HCV) is a leading cause of chronic liver disease world‐
wide. This paper examines our current understanding of the complex relationship between …

Hepatitis C virus: strategies to evade antiviral responses

NS Gokhale, C Vazquez, SM Horner - Future virology, 2014 - Taylor & Francis
Hepatitis C virus (HCV) causes chronic liver disease and poses a major clinical and
economic burden worldwide. HCV is an RNA virus that is sensed as nonself in the infected …

Hepatitis C virus infection: when silence is deception

V Racanelli, B Rehermann - Trends in immunology, 2003 - cell.com
Hepatitis C virus (HCV) uses complex and unique mechanisms to prevent, evade or subvert
innate and adaptive immune responses and to establish persistent infection and chronic …

Immune responses in hepatitis C virus infection and mechanisms of hepatitis C virus persistence

K Hiroishi, T Ito, M Imawari - Journal of gastroenterology and …, 2008 - Wiley Online Library
Immune responses against hepatitis C virus (HCV) play a crucial role in the pathogenesis of
chronic hepatitis C. HCV infection often persists and leads to chronic hepatitis and …