Moderate-Intensity and High-Intensity Interval Exercise Training Offer Equal Cardioprotection, with Different Mechanisms, during the Development of Type 2 Diabetes …

S D'Haese, L Claes, I de Laat, S Van Campenhout… - Nutrients, 2024 - mdpi.com
Endurance exercise training is a promising cardioprotective strategy in type 2 diabetes
mellitus (T2DM), but the impact of its intensity is not clear. We aimed to investigate whether …

Moderate-and High-Intensity Endurance Training Alleviate Diabetes-Induced Cardiac Dysfunction in Rats

S D'Haese, M Verboven, L Evens, D Deluyker… - Nutrients, 2023 - mdpi.com
Exercise training is an encouraging approach to treat cardiac dysfunction in type 2 diabetes
(T2DM), but the impact of its intensity is not understood. We aim to investigate whether and …

Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice

Z Pei, R Zhou, W Yao, S Dong, Y Liu, Z Gao - Iscience, 2023 - cell.com
Type 2 diabetes mellitus (T2DM) usually develop myocardial injury and that exercise may
have a positive effect on cardiac function. However, the effect of exercise intensity on cardiac …

Exercise training promotes cardioprotection through oxygen-sparing action in high fat-fed mice

J Lund, AD Hafstad, NT Boardman… - American Journal …, 2015 - journals.physiology.org
Although exercise training has been demonstrated to have beneficial cardiovascular effects
in diabetes, the effect of exercise training on hearts from obese/diabetic models is unclear. In …

Highlighting the effects of high-intensity interval training on the changes associated with hypertrophy, apoptosis, and histological proteins of the heart of old rats with …

M Rami, A Ahmadi Hekmatikar, S Rahdar… - Scientific Reports, 2024 - nature.com
T2DM is known to cause disturbances in glucose homeostasis and negative changes in the
heart muscle, while aging and diabetes are recognized risk factors for CVD. Given this, our …

High-Intensity Interval Training is as Efficient as Moderate Intensity Training in Reversing Diabetic Cardiomyopathy

M Verboven, L Evens, D Deluyker, D Colson… - Circulation, 2018 - Am Heart Assoc
Introduction: Type 2 Diabetes Mellitus (T2DM) is affecting more than 400 million people
worldwide and leads to diabetic cardiomyopathy. Exercise intervention is a low cost and …

High-and moderate-intensity training normalizes ventricular function and mechanoenergetics in mice with diet-induced obesity

AD Hafstad, J Lund, E Hadler-Olsen, AC Höper… - Diabetes, 2013 - Am Diabetes Assoc
Although exercise reduces several cardiovascular risk factors associated with
obesity/diabetes, the metabolic effects of exercise on the heart are not well-known. This …

High intensity interval training improves diabetic cardiomyopathy via miR-1 dependent suppression of cardiomyocyte apoptosis in diabetic rats

M Delfan, M Delphan, MR Kordi, AA Ravasi… - Journal of Diabetes & …, 2020 - Springer
Purpose Diabetes and its complications such as diabetic cardiomyopathy still account for
significant morbidity and mortality. High-quality evidence was shown the importance of …

[HTML][HTML] Endurance Exercise Prevented Diabetic Cardiomyopathy through the Inhibition of Fibrosis and Hypertrophy in Rats

S Shabab, M Mahmoudabady… - Reviews in …, 2024 - imrpress.com
Background: Exercise training could be essential in preventing pathological cardiac
remodeling in diabetes. Therefore, the effects of moderate-intensity continuous training …

Endurance Exercise Prevented Diabetic Cardiomyopathy through the Inhibition of Cardiac Hypertrophy and Fibrosis in Rats

S Shabab, M Mahmoudabady… - Available at SSRN … - papers.ssrn.com
Introduction: Exercise training could be considered an important strategy in preventing
cardiac pathologic remodeling in diabetes. This research aimed to investigate the effects of …