[HTML][HTML] Proteome-Wide Search Reveals Unexpected RNA-Binding Proteins in Saccharomyces cerevisiae

NG Tsvetanova, DM Klass, J Salzman, PO Brown - PloS one, 2010 - journals.plos.org
The vast landscape of RNA-protein interactions at the heart of post-transcriptional regulation
remains largely unexplored. Indeed it is likely that, even in yeast, a substantial fraction of the …

[HTML][HTML] Diverse RNA-binding proteins interact with functionally related sets of RNAs, suggesting an extensive regulatory system

DJ Hogan, DP Riordan, AP Gerber, D Herschlag… - PLoS …, 2008 - journals.plos.org
RNA-binding proteins (RBPs) have roles in the regulation of many post-transcriptional steps
in gene expression, but relatively few RBPs have been systematically studied. We searched …

Quantitative proteomic analysis reveals concurrent RNA–protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae

DM Klass, M Scheibe, F Butter, GJ Hogan… - Genome …, 2013 - genome.cshlp.org
A growing body of evidence supports the existence of an extensive network of RNA-binding
proteins (RBPs) whose combinatorial binding affects the post-transcriptional fate of every …

[HTML][HTML] A screen for RNA-binding proteins in yeast indicates dual functions for many enzymes

T Scherrer, N Mittal, SC Janga, AP Gerber - PloS one, 2010 - journals.plos.org
Hundreds of RNA-binding proteins (RBPs) control diverse aspects of post-transcriptional
gene regulation. To identify novel and unconventional RBPs, we probed high-density …

Identification of RNA recognition elements in the Saccharomyces cerevisiae transcriptome

DP Riordan, D Herschlag, PO Brown - Nucleic acids research, 2011 - academic.oup.com
Post-transcriptional regulation of gene expression, including mRNA localization, translation
and decay, is ubiquitous yet still largely unexplored. How is the post-transcriptional …

In silico characterization and prediction of global protein–mRNA interactions in yeast

V Pancaldi, J Bähler - Nucleic acids research, 2011 - academic.oup.com
Post-transcriptional gene regulation is mediated through complex networks of protein–RNA
interactions. The targets of only a few RNA binding proteins (RBPs) are known, even in the …

Transcriptome-wide discovery of coding and noncoding RNA-binding proteins

R Huang, M Han, L Meng… - Proceedings of the …, 2018 - National Acad Sciences
Transcriptome-wide identification of RNA-binding proteins (RBPs) is a prerequisite for
understanding the posttranscriptional gene regulation networks. However, proteomic …

Unconventional RNA‐binding proteins: an uncharted zone in RNA biology

WS Albihlal, AP Gerber - FEBS letters, 2018 - Wiley Online Library
The RNA‐binding proteins play essential roles in the post‐transcriptional regulation of gene
expression. While hundreds of RNA‐binding proteins can be predicted computationally, the …

Advances and challenges in the detection of transcriptome‐wide protein–RNA interactions

EC Wheeler, EL Van Nostrand… - Wiley Interdisciplinary …, 2018 - Wiley Online Library
RNA binding proteins (RBPs) play key roles in determining cellular behavior by
manipulating the processing of target RNAs. Robust methods are required to detect the …

Dissecting the expression dynamics of RNA-binding proteins in posttranscriptional regulatory networks

N Mittal, N Roy, MM Babu… - Proceedings of the …, 2009 - National Acad Sciences
In eukaryotic organisms, gene expression requires an additional level of coordination that
links transcriptional and posttranslational processes. Messenger RNAs have traditionally …