Podocytopathies are a spectrum of glomerular diseases characterized by podocyte cell
injury mediated by genetic, immunological, infectious, or toxic insults, which result in foot …

A spectrum of proteinuric glomerular diseases results from podocyte abnormalities. The
understanding of these podocytopathies has greatly expanded in recent years, particularly …

Background Hematuria is frequently present in podocytopathies, but its significance and
prognostic value is not well described in these proteinuric kidney diseases. This study …

Podocytopathies are glomerular disorders in which podocyte injury drives proteinuria and
progressive kidney disease. They encompass a broad spectrum of aetiologies, resulting in …

Podocytopathies are the most common group of glomerular disorder leading to proteinuria.
On the basis of pathophysiology, light microscopic and ultrastructural evaluation, the …

Among renal syndromes caused by glomerular disorders, FSGS continues to pose the most
challenges in understanding its pathogenesis and therefore, in arriving at mechanism-based …

Contributions: Research idea and study design: CPL, NCM; data acquisition: CPL; data
analysis/interpretation: CPL, NCM; supervision or mentorship: PDW. Each author …

Background In 2003, the authors of this article met in the Nephrology Division at
Massachusetts General Hospital. At that time, Dr. Sever was studying the role of GTPase …

Podocyte injury is the initiating step in the pathway toward clinically evident forms of
nephrotic syndrome known as podocytopathies, represented as either minimal change …

Background: Glucocorticoid remains the treatment of choice in adult primary podocytopathy
(Minimal Change Disease, MCD and Focal Segmental Glomerulosclerosis, FSGS). The use …