Objective Elevated vascular risk and beta‐amyloid (Aβ) burden have been synergistically
associated with cognitive decline in preclinical Alzheimer's disease (AD), although the …

Objective Neuropathological studies have demonstrated that cerebrovascular disease and
Alzheimer disease (AD) pathology frequently co‐occur in older adults. The extent to which …

Background and objectives Vascular risk factors and elevated β-amyloid (Aβ) are commonly
observed together among older adults. Here, we examined the interactive vs independent …

Importance Identifying asymptomatic individuals at high risk of impending cognitive decline
because of Alzheimer disease is crucial for successful prevention of dementia. Vascular risk …

Cardiovascular disease (CVD) is associated with a higher risk of developing dementia.
Studies have found that vascular risk factors are associated with greater amyloid-β (Aβ) and …

Objective To determine whether vascular risk and Alzheimer disease (AD) biomarkers have
independent or synergistic effects on cognitive decline and whether vascular risk is …

Introduction Vascular factors increase the risk of Alzheimer's disease (AD). We investigated
the associations between such factors, longitudinal AD cerebrospinal fluid biomarkers, and …

Background: The rate of AD for African Americans (AAs) is 64% higher than for non-Hispanic
White Americans (Whites). It is hypothesized that poor peripheral vascular function, in …

Objective Midlife vascular risk factors (MVRFs) are associated with incident dementia, as are
amyloid β (Aβ) deposition and neurodegeneration. Whether vascular and Alzheimer disease …

Tau pathology and vascular dysfunction are important contributors to Alzheimer's disease
(AD), but vascular–tau associations and their effects on cognition are poorly understood. We …