Peripheral mechanism of cancer-induced bone pain

Y Yang, W Yang, R Zhang, Y Wang - Neuroscience Bulletin, 2024 - Springer
Cancer-induced bone pain (CIBP) is a type of ongoing or breakthrough pain caused by a
primary bone tumor or bone metastasis. CIBP constitutes a specific pain state with distinct …

[HTML][HTML] Neurophysiological mechanisms of cancer-induced bone pain

XQ Zheng, Y Wu, J Huang, AM Wu - Journal of Advanced Research, 2022 - Elsevier
Abstract Background Cancer-induced Bone Pain (CIBP) is an important factor affecting their
quality of life of cancer survivors. In addition, current clinical practice and scientific research …

Role of the bone microenvironment in the development of painful complications of skeletal metastases

SH Park, MR Eber, DB Widner, Y Shiozawa - Cancers, 2018 - mdpi.com
Cancer-induced bone pain (CIBP) is the most common and painful complication in patients
with bone metastases. It causes a significant reduction in patient quality of life. Available …

Mechanisms of cancer-induced bone pain

T Middlemiss, BJA Laird, MT Fallon - Clinical Oncology, 2011 - Elsevier
Cancer-induced bone pain (CIBP) is common and challenging to treat. Common therapies,
such as opioids, radiotherapy and bisphosphonates, are often only partially effective. CIBP …

New insights of nociceptor sensitization in bone cancer pain

B Hua, Y Gao, X Kong, L Yang, W Hou… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Numerous studies have shown that an intact CNS is required for the conscious
perception of cancer-induced bone pain (CIBP) and that changes in the CNS are clearly …

Cancer induced bone pain: current management and future perspectives

R Kapoor, AK Saxena, P Vasudev, D Sundriyal… - Medical Oncology, 2021 - Springer
Recent improvements in the therapeutic armamentarium of oncology by the addition of
targeted and immunotherapeutic agents have led to an increase in the life expectancy of …

Use of animal models in understanding cancer-induced bone pain

LM Slosky, TM Largent-Milnes… - Cancer growth and …, 2015 - journals.sagepub.com
Many common cancers have a propensity to metastasize to bone. Although malignancies
often go undetected in their native tissues, bone metastases produce excruciating pain that …

Cancer-induced bone pain: Mechanisms and models

AN Lozano-Ondoua, AM Symons-Liguori… - Neuroscience …, 2013 - Elsevier
Cancerous cells can originate in a number of different tissues such as prostate, breast and
lung, but often go undetected and are non-painful. Many types of cancers have a propensity …

[HTML][HTML] Mechanisms of cancer-induced bone pain

AN Lozano-Ondoua, AM Symons-Liguori… - Neuroscience …, 2013 - ncbi.nlm.nih.gov
Cancerous cells can originate in a number of different tissues such as prostate, breast and
lung, yet often go undetected and are non-painful. Many types of cancers will metastasize …

Cancer–nerve interplay in cancer progression and cancer-induced bone pain

T Yoneda, M Hiasa, T Okui, K Hata - Journal of Bone and Mineral …, 2023 - Springer
Introduction Cancer-induced bone pain (CIBP) is one of the most common and debilitating
complications associated with bone metastasis. Although our understanding of the precise …