Large-scale analysis of plasmid relationships through gene-sharing networks

M Tamminen, M Virta, R Fani… - Molecular Biology and …, 2012 - academic.oup.com
Plasmids are vessels of genetic exchange in microbial communities. They are known to
transfer between different host organisms and acquire diverse genetic elements from …

Characterization of antimicrobial resistance dissemination across plasmid communities classified by network analysis

A Yamashita, T Sekizuka, M Kuroda - Pathogens, 2014 - mdpi.com
The global clustering of gene families through network analysis has been demonstrated in
whole genome, plasmid, and microbiome analyses. In this study, we carried out a …

Large-scale network analysis captures biological features of bacterial plasmids

M Acman, L van Dorp, JM Santini, F Balloux - Nature communications, 2020 - nature.com
Many bacteria can exchange genetic material through horizontal gene transfer (HGT)
mediated by plasmids and plasmid-borne transposable elements. Here, we study the …

Analysis of plasmid genes by phylogenetic profiling and visualization of homology relationships using Blast2Network

M Brilli, A Mengoni, M Fondi, M Bazzicalupo, P Liò… - BMC …, 2008 - Springer
Background Phylogenetic methods are well-established bioinformatic tools for sequence
analysis, allowing to describe the non-independencies of sequences because of their …

Identification of bacterial plasmids based on mobility and plasmid population biology

MP Garcillán-Barcia, A Alvarado… - FEMS microbiology …, 2011 - academic.oup.com
Plasmids contain a backbone of core genes that remains relatively stable for long
evolutionary periods, making sense to speak about plasmid species. The identification and …

Plasmids persist in a microbial community by providing fitness benefit to multiple phylotypes

L Li, A Dechesne, JS Madsen, J Nesme… - The ISME …, 2020 - academic.oup.com
The current epidemic of antibiotic resistance has been facilitated by the wide and rapid
horizontal dissemination of antibiotic resistance genes (ARGs) in microbial communities …

The dilution effect limits plasmid horizontal transmission in multispecies bacterial communities

A Kottara, L Carrilero, E Harrison, JPJ Hall… - …, 2021 - microbiologyresearch.org
By transferring ecologically important traits between species, plasmids drive genomic
divergence and evolutionary innovation in their bacterial hosts. Bacterial communities are …

Plasmid detection, characterization, and ecology

K Smalla, S Jechalke, EM Top - Microbiology spectrum, 2015 - Am Soc Microbiol
Plasmids are important vehicles for rapid adaptation of bacterial populations to changing
environmental conditions. It is thought that to reduce the cost of plasmid carriage, only a …

Pathways for horizontal gene transfer in bacteria revealed by a global map of their plasmids

S Redondo-Salvo, R Fernández-López, R Ruiz… - Nature …, 2020 - nature.com
Plasmids can mediate horizontal gene transfer of antibiotic resistance, virulence genes, and
other adaptive factors across bacterial populations. Here, we analyze genomic composition …

The persistence potential of transferable plasmids

T Wang, L You - Nature communications, 2020 - nature.com
Conjugative plasmids can mediate the spread and maintenance of diverse traits and
functions in microbial communities. This role depends on the plasmid's ability to persist in a …