3′-Sialyllactose alleviates bone loss by regulating bone homeostasis
A Baek, D Baek, Y Cho, S Jo, J Kim, Y Hong… - Communications …, 2024 - nature.com
Osteoporosis is a common skeletal disease that results in an increased risk of fractures.
However, there is no definitive cure, warranting the development of potential therapeutic …
However, there is no definitive cure, warranting the development of potential therapeutic …
3′‐Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis
J Jeon, LJ Kang, KM Lee, C Cho… - Journal of Cellular …, 2018 - Wiley Online Library
Sialyllactose has specific physiological functions in a variety of tissues; however, its effects
on osteoarthritic development remain unknown. Here, we demonstrated the function of 3 …
on osteoarthritic development remain unknown. Here, we demonstrated the function of 3 …
Differing responses of osteogenic cell lines to β-glycerophosphate
OS Yevlashevskaya, BA Scheven, AD Walmsley… - Scientific Reports, 2023 - nature.com
Abstract Ascorbic acid (Asc), dexamethasone (Dex) and β-glycerophosphate (β-Gly) are
commonly used to promote osteogenic behaviour by osteoblasts in vitro. According to the …
commonly used to promote osteogenic behaviour by osteoblasts in vitro. According to the …
Sialylation of cell surface glycoconjugates is essential for osteoclastogenesis
M Takahata, N Iwasaki, H Nakagawa, Y Abe… - Bone, 2007 - Elsevier
Sialic acid, which is located at the end of the carbohydrate moiety of cell surface
glycoconjugates, is involved in many biologic responses, such as intercellular reactions and …
glycoconjugates, is involved in many biologic responses, such as intercellular reactions and …
[HTML][HTML] Sec-O-glucosylhamaudol promotes the osteogenesis of pre-osteoblasts via BMP2 and Wnt3a signaling
KR Park, HH Leem, YJ Kwon, IK Kwon, JT Hong… - Journal of Functional …, 2022 - Elsevier
The perennial herb Saposhnikovia divaricata SCHISCHKIN, used as a source of traditional
medicines, is known for its anti-bone erosion, anti-inflammatory, and analgesic effects. We …
medicines, is known for its anti-bone erosion, anti-inflammatory, and analgesic effects. We …
Glycosylation status of bone sialoprotein and its role in mineralization
L Xu, Z Zhang, X Sun, J Wang, W Xu, L Shi, J Lu… - Experimental cell …, 2017 - Elsevier
The highly glycosylated bone sialoprotein (BSP) is an abundant non-collagenous
phosphoprotein in bone which enhances osteoblast differentiation and new bone deposition …
phosphoprotein in bone which enhances osteoblast differentiation and new bone deposition …
Strontium‑containing α‑calcium sulfate hemihydrate promotes bone repair via the TGF‑β/Smad signaling pathway
Z Liu, Z Yu, H Chang, Y Wang… - Molecular …, 2019 - spandidos-publications.com
Calcium phosphate‑based bone substitutes have been widely used for bone repair,
augmentation and reconstruction in bone implant surgery. While some of these substitutes …
augmentation and reconstruction in bone implant surgery. While some of these substitutes …
Glycated-HSA inhibits osteoclastogenesis in RAW264. 7 cells depending on the glycating agents via downregulating RANKL-signaling
ANM Mamun-Or-Rashid, W Takabe, M Yagi… - Glycative Stress …, 2017 - jstage.jst.go.jp
Background: In humans, bone density is reduced with age while advanced glycation
endproducts (AGEs) formation and accumulation increases. Therefore, the effect of AGEs on …
endproducts (AGEs) formation and accumulation increases. Therefore, the effect of AGEs on …
Cystathionine γ-lyase–hydrogen sulfide induces runt-related transcription factor 2 sulfhydration, thereby increasing osteoblast activity to promote bone fracture healing
Y Zheng, F Liao, X Lin, F Zheng, J Fan… - Antioxidants & Redox …, 2017 - liebertpub.com
Abstract Aims: Hydrogen sulfide (H2S) plays an essential role in bone formation, in part, by
inhibiting osteoclast differentiation, maintaining mesenchymal stem cell osteogenesis ability …
inhibiting osteoclast differentiation, maintaining mesenchymal stem cell osteogenesis ability …