Risk stratification of endometrial cancer patients: FIGO stage, biomarkers and molecular classification

JC Kasius, JMA Pijnenborg, K Lindemann, D Forsse… - Cancers, 2021 - mdpi.com
Simple Summary Endometrial cancer (EC) is the most common gynaecologic malignancy in
developed countries. Most patients are sufficiently treated with removal of uterus, tubes and …

Incorporation of molecular characteristics into endometrial cancer management

L Vermij, V Smit, R Nout, T Bosse - Histopathology, 2020 - Wiley Online Library
Histopathological evaluation including subtyping and grading is the current cornerstone for
endometrial cancer (EC) classification. This provides clinicians with prognostic information …

Molecular classification of endometrial carcinoma on diagnostic specimens is highly concordant with final hysterectomy: earlier prognostic information to guide …

A Talhouk, LN Hoang, MK McConechy… - Gynecologic …, 2016 - Elsevier
Objective Categorization and risk stratification of endometrial carcinomas is inadequate;
histomorphologic assessment shows considerable interobserver variability, and risk of …

Improved risk assessment by integrating molecular and clinicopathological factors in early-stage endometrial cancer—combined analysis of the PORTEC cohorts

E Stelloo, RA Nout, EM Osse, IJ Jürgenliemk-Schulz… - Clinical cancer …, 2016 - AACR
Purpose: Recommendations for adjuvant treatment for women with early-stage endometrial
carcinoma are based on clinicopathologic features. Comprehensive genomic …

The TCGA molecular classification of endometrial cancer and its possible impact on adjuvant treatment decisions

M Alexa, A Hasenburg, MJ Battista - Cancers, 2021 - mdpi.com
Simple Summary The Proactive Molecular Risk Classifier for Endometrial Cancer (ProMisE)
is a recently developed tool to identify four distinct molecular subgroups of endometrial …

Role of genomic and molecular biology in the modulation of the treatment of endometrial cancer: narrative review and perspectives

I Cuccu, O D'Oria, L Sgamba, E De Angelis… - Healthcare, 2023 - mdpi.com
Endometrial cancer (EC) is one of the most common gynecological malignancies in Western
countries. Traditionally, loco-reginal dissemination and histological characteristics are the …

Molecular characterization of endometrial cancer and therapeutic implications

Z Chang, S Talukdar, SA Mullany… - Current opinion in …, 2019 - journals.lww.com
Molecular characterization of endometrial cancer into subgroups has prognostic and
therapeutic implications. Further development of an integrated molecular risk profile may …

A clinically applicable molecular-based classification for endometrial cancers

A Talhouk, MK McConechy, S Leung… - British journal of …, 2015 - nature.com
Background: Classification of endometrial carcinomas (ECs) by morphologic features is
inconsistent, and yields limited prognostic and predictive information. A new system for …

[HTML][HTML] Pathologic prognostic factors in endometrial carcinoma (other than tumor type and grade)

N Singh, L Hirschowitz, R Zaino… - International Journal …, 2019 - journals.lww.com
Although endometrial carcinoma (EC) is generally considered to have a good prognosis,
over 20% of women with EC die of their disease, with a projected increase in both incidence …

Prognostic biomarkers in endometrial cancer: a systematic review and meta-analysis

E Coll-de la Rubia, E Martinez-Garcia… - Journal of clinical …, 2020 - mdpi.com
Endometrial cancer (EC) is the sixth most common cancer in women worldwide and its
mortality is directly associated with the presence of poor prognostic factors driving tumor …