Efficacy and safety of EGFR-TKI combined with WBRT vs. WBRT alone in the treatment of brain metastases from NSCLC: a systematic review and meta-analysis

S Li, S Xu, L Li, Z Xue, L He - Frontiers in Neurology, 2024 - frontiersin.org
Background The efficacy and safety of combining epidermal growth factor receptor tyrosine
kinase inhibitors (EGFR-TKIs) with whole-brain radiotherapy (WBRT) for treating brain …

Efficacy and safety of WBRT+ EGFR‐TKI versus WBRT only in the treatment of NSCLC patients with brain metastasis: An updated meta‐analysis

K Zhou, X Cai, X Wang, X Lan, X Zhang - Thoracic Cancer, 2022 - Wiley Online Library
Background To investigate the efficacy and safety of whole brain radiotherapy (WBRT)
combined with epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) versus …

Whole Brain Radiotherapy (WBRT) plus EGFR tyrosine kinase inhibitors (TKIs) versus WBRT alone for brain metastases (BMs) in non-small cell lung cancer (NSCLC) …

L Liu, M Yang, J Guan, YW Zhang, Q Li, Y Zhang… - 2015 - ascopubs.org
e19060 Background: NSCLC accounts for 85%-90% of lung cancers, in which brain
metastases (BMs) occur in 20–40% of all NSCLC cases. WBRT is the standard treatment for …

Efficacy and Safety of EGFR Tyrosine Kinase Inhibitors Combined with Cranial Radiotherapy for Brain Metastases from Non‐Small‐Cell Lung Cancer: A Protocol for a …

Y Ge, B Xu, H Wang, J Gao, X Zhang… - BioMed Research …, 2022 - Wiley Online Library
Introduction. Brain metastases (BMs) are common in non‐small‐cell lung cancer (NSCLC),
which leads to a poor prognosis. As the two most effective strategies available, the use of …

[HTML][HTML] Efficacy and safety of radiotherapy plus EGFR-TKIs in NSCLC patients with brain metastases: a meta-analysis of published data

X Wang, Y Xu, W Tang, L Liu - Translational oncology, 2018 - Elsevier
Background: The role of radiotherapy (RT) combined with epidermal growth factor receptor
tyrosine kinase inhibitors (EGFR-TKIs) in non-small cell lung cancer (NSCLC) patients with …

Combination of EGFR-Directed Tyrosine Kinase Inhibitors (EGFR-TKI) with Radiotherapy in Brain Metastases from Non-Small Cell Lung Cancer: A 2010-2019 …

S Saxena, A Khosla, A Ozair, R Kotecha… - …, 2023 - scholarlycommons.baptisthealth.net
Introduction: Traditionally, brain metastases have been treated with stereotactic radiosurgery
(SRS), whole-brain radiation (WBRT), and/or surgical resection. Non-small cell lung cancers …

Combination of EGFR-Directed Tyrosine Kinase Inhibitors (EGFR-TKI) with Radiotherapy in Brain Metastases from Non-Small Cell Lung Cancer: A 2010–2019 …

V Tatineni, PJ O'Shea, S Saxena, AA Khosla, A Ozair… - Cancers, 2023 - mdpi.com
Simple Summary Radiotherapy, in the form of either whole-brain radiotherapy (WBRT) or
stereotactic radiosurgery (SRS), continues as the standard of care for patients of non-small …

Upfront cranial radiotherapy vs. EGFR tyrosine kinase inhibitors alone for the treatment of brain metastases from non-small-cell lung cancer: a meta-analysis of 1465 …

XJ Du, SM Pan, SZ Lai, XN Xu, ML Deng… - Frontiers in …, 2018 - frontiersin.org
Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) is
revolutionizing the management of brain metastases (BMs). This study was to explore the …

Combining Whole‐Brain Radiotherapy with Gefitinib/Erlotinib for Brain Metastases from Non‐Small‐Cell Lung Cancer: A Meta‐Analysis

M Zheng, H Sun, J Xu, G Yang, L Huo… - BioMed Research …, 2016 - Wiley Online Library
Background. To comprehensively assess the efficacy and safety of whole‐brain
radiotherapy (WBRT) combined with gefitinib/erlotinib for treatment of brain metastases (BM) …

Radiotherapy plus EGFR TKIs in non‐small cell lung cancer patients with brain metastases: an update meta‐analysis

T Jiang, W Min, Y Li, Z Yue, C Wu, C Zhou - Cancer Medicine, 2016 - Wiley Online Library
Brain metastasis (BM) is the common complication of non‐small cell lung cancer (NSCLC)
with a poor prognosis and dismal survival rate. This update meta‐analysis aimed to derive a …