[HTML][HTML] DNA methylation: a historical perspective
AL Mattei, N Bailly, A Meissner - Trends in Genetics, 2022 - cell.com
In 1925, 5-methylcytosine was first reported in bacteria. However, its biological importance
was not intuitive for several decades. After this initial lag, the ubiquitous presence of this …
was not intuitive for several decades. After this initial lag, the ubiquitous presence of this …
Exposing the DNA methylome iceberg
MN Ndlovu, H Denis, F Fuks - Trends in biochemical sciences, 2011 - cell.com
DNA methylation was the first epigenetic modification discovered. Until recently,
comprehensive coverage of the composition and distribution of methylated cytosines across …
comprehensive coverage of the composition and distribution of methylated cytosines across …
DNA methylation: shared and divergent features across eukaryotes
Chemical modification of nucleotide bases in DNA provides one mechanism for conveying
information in addition to the genetic code. 5-methylcytosine (5mC) represents the most …
information in addition to the genetic code. 5-methylcytosine (5mC) represents the most …
Advances in genome-wide DNA methylation analysis
R Gupta, A Nagarajan, N Wajapeyee - Biotechniques, 2010 - Taylor & Francis
The covalent DNA modification of cytosine at position 5 (5-methylcytosine; 5mC) has
emerged as an important epigenetic mark most commonly present in the context of CpG …
emerged as an important epigenetic mark most commonly present in the context of CpG …
[HTML][HTML] The DNA methylome
M Pelizzola, JR Ecker - FEBS letters, 2011 - Elsevier
Methylation of cytosines is a pervasive feature of eukaryotic genomes and an important
epigenetic layer that is fundamental for cellular differentiation processes and control of …
epigenetic layer that is fundamental for cellular differentiation processes and control of …
Conservation and divergence in eukaryotic DNA methylation
Cytosine methylation is a com-mon DNA modification found in most eukaryotic organisms
including plants, animals, and fungi (1, 2). The addition of a methyl group to cytosine …
including plants, animals, and fungi (1, 2). The addition of a methyl group to cytosine …
The methylome: approaches for global DNA methylation profiling
S Beck, VK Rakyan - Trends in Genetics, 2008 - cell.com
DNA methylation plays a critical role in genome function both in health and disease. Almost
60 years after the discovery of 5-methyl cytosine and∼ 25 years since the discovery that …
60 years after the discovery of 5-methyl cytosine and∼ 25 years since the discovery that …
Identifying 5-methylcytosine and related modifications in DNA genomes
T Rein, ML DePamphilis, H Zorbas - Nucleic acids research, 1998 - academic.oup.com
Intense interest in the biological roles of DNA methylation, particularly in eukaryotes, has
produced at least eight different methods for identifying 5-methylcytosine and related …
produced at least eight different methods for identifying 5-methylcytosine and related …
Mechanisms of DNA methylation and demethylation in mammals
G Auclair, M Weber - Biochimie, 2012 - Elsevier
Cytosine methylation is an epigenetically propagated DNA modification that can modify how
the DNA molecule is recognized and expressed. DNA methylation undergoes extensive …
the DNA molecule is recognized and expressed. DNA methylation undergoes extensive …
Non-canonical functions of the DNA methylome in gene regulation
JP Reddington, S Pennings, RR Meehan - Biochemical Journal, 2013 - portlandpress.com
Methylation of the cytosine base in DNA, DNA methylation, is an essential epigenetic mark
in mammals that contributes to the regulation of transcription. Several advances have been …
in mammals that contributes to the regulation of transcription. Several advances have been …