The TRPV1 ion channel is a neuronal sensor that plays an important role in nociception and
neuropathic as well as inflammatory pain. In clinical trials, hyperthermia and thermo …

Identification of novel antagonists targeting the transient receptor potential vanilloid type 1
(TRPV1) protein has been at the forefront of pain research in the pharmaceutical industry for …

The thermosensory transient receptor potential vanilloid 1 channel (TRPV1) is a polymodal
receptor activated by physical and chemical stimuli. TRPV1 activity is drastically potentiated …

Following the cloning and characterization of the transient receptor potential vanilloid 1
(TRPV1), a growing body of research has identified the important role of TRPV1 and related …

Introduction: Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation
channel with high permeability to calcium, which is widely expressed in the central nervous …

The neuropathic pain market in the United States is expected to nearly double from today's
$2.6 billion to $5 billion by 2018 according to a recent report by the market research firm …

With 462 reviews over the past decade, Transient Receptor Potential (TRP) channels
arguably represent one of today's most extensively reviewed pharmacological targets. The …

Transient receptor potential vanilloid 1 (TRPV1) is a multifunctional ion channel playing
important roles in a numerous biological processes including the regulation of body …

Introduction: Transient receptor potential vanilloid type 1 (TRPV1) is a nonselective cation
channel that can be activated by noxious heat, low pH and vanilloid compounds such as …

Efforts on developing transient receptor potential vanilloid 1 (TRPV1) drugs for pain
management have been hampered by deleterious hypo-or hyperthermia caused by TRPV1 …