[HTML][HTML] Strategies in the delivery of Cas9 ribonucleoprotein for CRISPR/Cas9 genome editing
S Zhang, J Shen, D Li, Y Cheng - Theranostics, 2021 - ncbi.nlm.nih.gov
CRISPR/Cas9 genome editing has gained rapidly increasing attentions in recent years,
however, the translation of this biotechnology into therapy has been hindered by efficient …
however, the translation of this biotechnology into therapy has been hindered by efficient …
Progress of delivery methods for CRISPR-Cas9
Introduction Gene therapy is becoming increasingly common in clinical practice, giving hope
for the correction of a wide range of human diseases and defects. The CRISPR/Cas9 …
for the correction of a wide range of human diseases and defects. The CRISPR/Cas9 …
Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities
L Li, S Hu, X Chen - Biomaterials, 2018 - Elsevier
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas
(CRISPR-associated) genome editing systems have become one of the most robust …
(CRISPR-associated) genome editing systems have become one of the most robust …
Direct cytosolic delivery of CRISPR/Cas9-ribonucleoprotein for efficient gene editing
Genome editing through the delivery of CRISPR/Cas9-ribonucleoprotein (Cas9-RNP)
reduces unwanted gene targeting and avoids integrational mutagenesis that can occur …
reduces unwanted gene targeting and avoids integrational mutagenesis that can occur …
Delivery of CRISPR/Cas9 by novel strategies for gene therapy
Precise editing of the genome of a living body is a goal pursued by scientists in many fields.
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas …
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas …
CRISPR/Cas9 delivery system engineering for genome editing in therapeutic applications
H Cheng, F Zhang, Y Ding - Pharmaceutics, 2021 - mdpi.com
The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein
9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform …
9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform …
Carrier strategies boost the application of CRISPR/Cas system in gene therapy
Z Xu, Q Wang, H Zhong, Y Jiang, X Shi, B Yuan… - …, 2022 - Wiley Online Library
Emerging clustered regularly interspaced short palindromic repeat/associated protein
(CRISPR/Cas) genome editing technology shows great potential in gene therapy. However …
(CRISPR/Cas) genome editing technology shows great potential in gene therapy. However …
Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications
The CRISPR-Cas9 genome-editing system is a part of the adaptive immune system in
archaea and bacteria to defend against invasive nucleic acids from phages and plasmids …
archaea and bacteria to defend against invasive nucleic acids from phages and plasmids …
[HTML][HTML] In vivo delivery of CRISPR-Cas9 therapeutics: Progress and challenges
Within less than a decade since its inception, CRISPR-Cas9-based genome editing has
been rapidly advanced to human clinical trials in multiple disease areas. Although it is highly …
been rapidly advanced to human clinical trials in multiple disease areas. Although it is highly …
Synthetic multi-layer nanoparticles for CRISPR-Cas9 genome editing
The clustered regularly interspaced short palindromic repeat (CRISPR) has great potential
to revolutionize biomedical research and disease therapy. The specific and efficient genome …
to revolutionize biomedical research and disease therapy. The specific and efficient genome …