Purpose Paclitaxel (PTX) is a first-line chemotherapeutic agent for treating ovarian cancer.
However, PTX resistance has become a major obstacle in ovarian cancer therapy. The …

Chemoresistance is a major cause of high mortality and poor survival in patients with
ovarian cancer (OVCA). Understanding the mechanisms of chemoresistance is urgently …

Purpose Breast cancer (BC) is one of the leading causes of cancer-related deaths.
Chemoresistance of BC remains a major unmet clinical obstacle. TUG1 (taurine-upregulated …

Long non-coding RNAs (lncRNAs) have been demonstrated to influence the
chemoresistance of colorectal cancer (CRC). Therefore, the study is designed to investigate …

Objective To investigate the underlying mechanism of lncRNA TUG1 in pancreatic ductal
adenocarcinoma (PDAC). Methods The expression of TUG1 was defined by qRT-PCR. The …

Ovarian cancer is the fifth leading cause of cancer-related death in women worldwide, and
recent studies have highlighted the role of long non-coding RNAs (lncRNAs) in cancer …

Purpose Clear cell renal cell carcinoma (ccRCC) is a common urological carcinoma in
adults. Long non-coding RNA (lncRNA) taurine-upregulated gene 1 (TUG1) has been …

Background: Long non-coding RNA taurine up-regulated gene 1 (TUG1) was reportedly
involved in initiation and development of several cancers. However, its function and …

Background Accumulating evidence indicates that the long noncoding RNA taurine
upregulated gene 1 (TUG1) plays a critical role in cancer progression and metastasis …

Colorectal cancer (CRC) is a common malignancy, most of which remain unresponsive to
chemotherapy. Methotrexate (MTX) is one of the earliest cytotoxic drugs and serves as an …