Monogenic kidney diseases are involved in up to 15% of end-stage kidney diseases in
adults, and in 70% of pediatric patients. When these disorders lead to kidney failure, kidney …

Monogenic nephrotic syndrome (nephrotic syndrome caused by a single gene defect) is
responsible for only a small percentage of cases of nephrotic syndrome, but information from …

Monogenic forms of heritable kidney disease account for a significant proportion of chronic
kidney disease (CKD) across both pediatric and adult patient populations and up to 11% of …

Inherited kidney diseases (IKDs) are among the leading causes of early-onset chronic
kidney disease (CKD) and are responsible for at least 10–15% of cases of kidney …

Nephrotic syndrome (NS) defines a clinical entity of proteinuria, hypoproteinemia, and
edema. Proteinuria is caused by an acquired or genetic defect in the glomerular filtration …

Growth in knowledge of the genetics of kidney disease has revealed that significant
percentages of patients with diverse types of nephropathy have causative mutations …

In this review, we describe the multidisciplinary, multidimensional care required to optimize
outcomes for pediatric transplant recipients with rare genetic kidney diseases. Transplant …

Living donor transplantation is the preferred treatment for end-stage kidney disease (ESKD).
While living donor transplantation generally substantially enhances the quality of life and …

Background Often only chronic kidney disease (CKD) patients with high likelihood of genetic
disease are offered genetic testing. Early genetic testing could obviate the need for kidney …

Better outcomes for living donor transplantation, together with the shortened waiting time
and the increasing gap between supply and demand for kidneys for transplantation, has led …