Beyond the well-known function of poly (A) tail length in mRNA stability, recent years have
witnessed an explosion of information about how changes in tail length and the selection of …

While the phenomenon of polyadenylation has been well-studied, the dynamics of poly (A)
tail size and its impact on transcript function and cell biology are less well-appreciated. The …

Poly (A) tails have long been known as stable 3′ modifications of eukaryotic mRNAs,
added during nuclear pre‐mRNA processing. It is now appreciated that this modification is …

In eukaryotes, poly (A) tails are present on almost every mRNA. Early experiments led to the
hypothesis that poly (A) tails and the cytoplasmic polyadenylate-binding protein (PABPC) …

Poly (A) tails are non-templated additions of adenosines at the 3′ ends of most eukaryotic
mRNAs. In the nucleus, these RNAs are co-transcriptionally cleaved at a poly (A) site and …

Abstract The 3′‐end poly (A) tail is an important and potent feature of most mRNA
molecules that affects mRNA fate and translation efficiency. Polyadenylation is a …

Poly (A) tails are important elements in mRNA translation and stability, although recent
genome-wide studies have concluded that poly (A) tail length is generally not associated …

The poly (A) tail present at the 3′ end of most eukaryotic mRNAs can play a critical role in
message translation and stability. Therefore, identifying alterations in poly (A) tail length can …

Message RNA poly (A) tails are vital for their function and regulation. However, the full-
length sequence of mRNA isoforms with their poly (A) tails remains undetermined. Here, we …

Poly (A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but
difficulties in globally measuring poly (A)-tail lengths have impeded greater understanding of …